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Myeloproliferative Neoplasia
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Manage episode 466680181 series 3320136
Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myeloproliferative Neoplasms, covering their pathophysiology, clinical presentation, and management. We discuss Polycythemia Vera, Essential Thrombocythemia, Chronic Myeloid Leukemia, and Primary Myelofibrosis, focusing on key mutations like JAK2, CALR, and BCR-ABL. Our discussion includes diagnostic tools such as peripheral blood smear, bone marrow biopsy, and laboratory markers like erythropoietin levels, leukocyte alkaline phosphatase, and BCR-ABL testing. We also review treatment options, including tyrosine kinase inhibitors, cytoreductive therapy, and JAK inhibitors, as well as complications like thrombosis, bleeding, and transformation to acute leukemia. This episode provides a high-yield review for exams and clinical practice. Enjoy the episode, and support us below!
Bab
1. Myeloproliferative Neoplasia (00:00:00)
2. [Ad] Diabetes dialogues podcast (00:15:42)
3. (Cont.) Myeloproliferative Neoplasia (00:16:20)
89 episod
Fetch error
Hmmm there seems to be a problem fetching this series right now. Last successful fetch was on December 04, 2025 17:04 ()
What now? This series will be checked again in the next day. If you believe it should be working, please verify the publisher's feed link below is valid and includes actual episode links. You can contact support to request the feed be immediately fetched.
Manage episode 466680181 series 3320136
Ninja Nerds!
Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we explore Myeloproliferative Neoplasms, covering their pathophysiology, clinical presentation, and management. We discuss Polycythemia Vera, Essential Thrombocythemia, Chronic Myeloid Leukemia, and Primary Myelofibrosis, focusing on key mutations like JAK2, CALR, and BCR-ABL. Our discussion includes diagnostic tools such as peripheral blood smear, bone marrow biopsy, and laboratory markers like erythropoietin levels, leukocyte alkaline phosphatase, and BCR-ABL testing. We also review treatment options, including tyrosine kinase inhibitors, cytoreductive therapy, and JAK inhibitors, as well as complications like thrombosis, bleeding, and transformation to acute leukemia. This episode provides a high-yield review for exams and clinical practice. Enjoy the episode, and support us below!
Bab
1. Myeloproliferative Neoplasia (00:00:00)
2. [Ad] Diabetes dialogues podcast (00:15:42)
3. (Cont.) Myeloproliferative Neoplasia (00:16:20)
89 episod
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