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Can an Inflammation Blood Test Detect Heart Disease Early?

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Manage episode 446181267 series 3555208
Kandungan disediakan oleh MedEvidence Articles. Semua kandungan podcast termasuk episod, grafik dan perihalan podcast dimuat naik dan disediakan terus oleh MedEvidence Articles atau rakan kongsi platform podcast mereka. Jika anda percaya seseorang menggunakan karya berhak cipta anda tanpa kebenaran anda, anda boleh mengikuti proses yang digariskan di sini https://ms.player.fm/legal.

In this week's episode we take a closer look at the high-sensitivity C-reactive protein (hs-CRP) test, a powerful tool which may help assess cardiovascular risk. It is a biomarker of inflammation, and hs-CRP’s ability to predict heart disease is both fascinating and complex. We’ll explore how chronic inflammation affects the heart, what high hs-CRP levels can reveal about your health, and how lifestyle and medical changes like exercise and statins can help lower your risk.
Share with a friend. Rate, Review, and Subscribe to MedEvidence Articles to be notified when new episodes are released.

Follow us on Social Media:

Facebook
Instagram
Twitter
LinkedIn
Tiktok
Youtube

For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence podcast. www.MedEvidence.com

Thank you for listening!

References:

Bassuk, S. S., Rifai, N., & Ridker, P. M. (2004). High-sensitivity C-reactive protein: clinical importance. Current problems in cardiology, 29(8), 439-493.

Bray, C., Bell, L. N., Liang, H., Haykal, R., Kaiksow, F., Mazza, J. J., & Yale, S. H. (2016). Erythrocyte sedimentation rate and C-reactive protein measurements and their relevance in clinical medicine. Wmj, 115(6), 317-21.

Labcorp. (n.d.). Inflammation (hs-CRP) test. Labcorp OnDemand, [Website]. Accessed 14 October, 2024. https://www.ondemand.labcorp.com/lab-tests/inflammation-hs-crp-test

Mojca, S. (2003). Atherothrombosis: Pathogenesis of Cardiovascular Disease. EJIFCC, 14(2), 47. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169144/

Ridker, P. M. (2016). A test in context: high-sensitivity C-reactive protein. Journal of the American College of Cardiology, 67(6), 712-723. https://www.jacc.org/doi/full/10.1016/j.jacc.2015.11.037

Ridker, P. M., Danielson, E., Fonseca, F. A., Genest, J., Gotto Jr, A. M., Kastelein, J. J., ... & Glynn, R. J. (2008). Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. New England journal of medicine, 359(21), 2195-2207. https://www.nejm.org/doi/full/10.1056/NEJMoa0807646

Ridker, P. M., Rifai, N., Clearfield, M., Downs, J. R., Weis, S. E., Miles, J. S., & Gotto Jr, A. M. (2001). Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. New England Journal of Medicine, 344(26), 1959-1965. https://www.nejm.org/doi/full/10.1056/NEJM200106283442601

Sproston, N. R., & Ashworth, J. J. (2018). Role of C-reactive protein at sites of inflammation and infection. Frontiers in immunology, 9, 754. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908901/

Thompson, D., Pepys, M. B., & Wood, S. P. (1999). The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure, 7(2), 169-177. https://www.cell.com/structure/fulltext/S0969-2126(99)80023-9

  continue reading

35 episod

Artwork
iconKongsi
 
Manage episode 446181267 series 3555208
Kandungan disediakan oleh MedEvidence Articles. Semua kandungan podcast termasuk episod, grafik dan perihalan podcast dimuat naik dan disediakan terus oleh MedEvidence Articles atau rakan kongsi platform podcast mereka. Jika anda percaya seseorang menggunakan karya berhak cipta anda tanpa kebenaran anda, anda boleh mengikuti proses yang digariskan di sini https://ms.player.fm/legal.

In this week's episode we take a closer look at the high-sensitivity C-reactive protein (hs-CRP) test, a powerful tool which may help assess cardiovascular risk. It is a biomarker of inflammation, and hs-CRP’s ability to predict heart disease is both fascinating and complex. We’ll explore how chronic inflammation affects the heart, what high hs-CRP levels can reveal about your health, and how lifestyle and medical changes like exercise and statins can help lower your risk.
Share with a friend. Rate, Review, and Subscribe to MedEvidence Articles to be notified when new episodes are released.

Follow us on Social Media:

Facebook
Instagram
Twitter
LinkedIn
Tiktok
Youtube

For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence podcast. www.MedEvidence.com

Thank you for listening!

References:

Bassuk, S. S., Rifai, N., & Ridker, P. M. (2004). High-sensitivity C-reactive protein: clinical importance. Current problems in cardiology, 29(8), 439-493.

Bray, C., Bell, L. N., Liang, H., Haykal, R., Kaiksow, F., Mazza, J. J., & Yale, S. H. (2016). Erythrocyte sedimentation rate and C-reactive protein measurements and their relevance in clinical medicine. Wmj, 115(6), 317-21.

Labcorp. (n.d.). Inflammation (hs-CRP) test. Labcorp OnDemand, [Website]. Accessed 14 October, 2024. https://www.ondemand.labcorp.com/lab-tests/inflammation-hs-crp-test

Mojca, S. (2003). Atherothrombosis: Pathogenesis of Cardiovascular Disease. EJIFCC, 14(2), 47. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169144/

Ridker, P. M. (2016). A test in context: high-sensitivity C-reactive protein. Journal of the American College of Cardiology, 67(6), 712-723. https://www.jacc.org/doi/full/10.1016/j.jacc.2015.11.037

Ridker, P. M., Danielson, E., Fonseca, F. A., Genest, J., Gotto Jr, A. M., Kastelein, J. J., ... & Glynn, R. J. (2008). Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. New England journal of medicine, 359(21), 2195-2207. https://www.nejm.org/doi/full/10.1056/NEJMoa0807646

Ridker, P. M., Rifai, N., Clearfield, M., Downs, J. R., Weis, S. E., Miles, J. S., & Gotto Jr, A. M. (2001). Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. New England Journal of Medicine, 344(26), 1959-1965. https://www.nejm.org/doi/full/10.1056/NEJM200106283442601

Sproston, N. R., & Ashworth, J. J. (2018). Role of C-reactive protein at sites of inflammation and infection. Frontiers in immunology, 9, 754. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908901/

Thompson, D., Pepys, M. B., & Wood, S. P. (1999). The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure, 7(2), 169-177. https://www.cell.com/structure/fulltext/S0969-2126(99)80023-9

  continue reading

35 episod

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