The Critical Care Reviews Podcast discusses the biggest critical care trials, either planned or in progress, with their chief investigators. It's hosted by Rob Mac Sweeney, an intensivist in Belfast, Northern Ireland. We also release audio versions of the presentations from the Critical Care Reviews Meetings and ad hoc livestreams
…
continue reading
Rob Mac Sweeney chats with Jessica Spence about the B-FREE trial, investigating benzodiazepine-free anaesthesia for the prevention of delirium in cardiac surgeryOleh Rob Mac Sweeney
…
continue reading
1
Beyond Platform Trials Panel Discussion
1:04:09
1:04:09
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:04:09
Bala Venkatesh (Brisbane) hosts a panel discussion entitled "Beyond Platform Trials" at the Critical Care Reviews Meeting 2023. The panellists include Bronagh Blackwood (Belfast), Susan Rowell (Chicago), Fernando Zampieri (Edmonton), Marion Campbell (Aberdeen), David Harrison (London), Roger Lewis (Los Angeles), Derek Angus (Pittsburgh) & Kathy Row…
…
continue reading
1
Causality Panel Discussion
1:00:52
1:00:52
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:00:52
Kathy Rowan (London) hosts a fascinating panel discussion on causality at the Critical Care Reviews Meeting 2023. The panellists include Bronwen Connolly (Belfast), Ewan Goligher (Toronto), Flavia Machado (Sao Paulo), Kath Maitland (Kalifi), John Norrie (Edinburgh), Victoria Cornelius (London), Andrew Althouse (Pittsburgh) and Chris Seymour (Pittsb…
…
continue reading
1
REMAP-CAP Trial Long Term Outcomes
47:09
47:09
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
47:09
Dr Lisa Higgins (Melbourne) presents the long term outcomes of the REMAP-CAP domains at the Critical Care Reviews Meeting 2023. Prof Howard Bauchner (Boston) delivers an editorial. Prof Christopher Seymour (Pittsburgh) chairs the session.Oleh Rob Mac Sweeney
…
continue reading
Nina Christine Andersen-Ranberg presents the AID-ICU trial, investigating haloperidol for the management of delirium in the ICU. Danny McAuley delivers an editorial. Anders Perner joins the discussion and the session is chaired by Paul Mouncey.Oleh Rob Mac Sweeney
…
continue reading
Prof Flavia Machado (Sao Paulo) delivers the John Hinds Lecture at the Critical Care Reviews Meeting 2023, describing the story of BRICNET, the Brazilian Critical Care Trials Group. The session commences with Dr Chris Nutt remembering our friend, Dr John Hinds.Oleh Rob Mac Sweeney
…
continue reading
You're listening to the audio version of the PROCOAG trial presentation from the Critical Care Reviews Meeting 2023. The PROCOAG trial investigated the efficacy and safety of early administration of 4-factor prothrombin complex concentrate in trauma patients at risk of massive transfusion. The trial is presented by Pierre Bouzat from Grenoble. Susa…
…
continue reading
You're listening to the audio version of the TEAM trial presentation from the Critical Care Reviews Meeting 2023. The TEAM trial investigated early active mobilisation in critically ill mechanically ventilated patients. The trial is presented by Carol Hodgson from Melbourne. Darren Taichman from Philadelphia, delivers the editorial. The session is …
…
continue reading
Matthew Semler (Nashville, USA) presents the PILOT trial at the Critical care Reviews Meeting 2023, in Titanic Belfast. The PILOT trial compared low, intermediate and high oxygenation targets in critically ill mechanically ventilated patients. Kath Maitland from Kigali, Kenya, delivers an independent editorial. The session is chaired by Chris Seymo…
…
continue reading
1
REMAP-CAP / LOVIT-COVID Vitamin C Trial
52:32
52:32
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
52:32
Dr Francois Lamontagne joins Rob Mac Sweeney to discuss the harmonised REMAP-CAP / LOVIT-COVID vitamin C trial. The trial was presented at the European Society of Intensive Care Medicine annual congress and simultaneously published in the New England Journal of Medicine.Oleh Rob Mac Sweeney
…
continue reading
Oleh Rob Mac Sweeney
…
continue reading
1
OXY-PICU Trial Presentation
1:20:30
1:20:30
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:20:30
Mark Peters and Doug Gould (both London) present the results of the OXY-PICU trial, comparing conservative with liberal oxygenation targets (SpO2 88-92% vs >94%) in critically ill children receiving invasive mechanical ventilation. Luregn Schlapbach (Zurich) delivers an independent editorial. They are joined by Victoria Cornelius (London), Bronagh …
…
continue reading
Scott Berry (Austin) and Danny McAuley (Belfast) join Rob Mac Sweeney to discuss the results of the statin domain of the REMAP-CAP trial, investigating 80mg once daily of simvastatin in critically ill patients with COVID-19.Oleh Rob Mac Sweeney
…
continue reading
1
UK-REBOA Trial Presentation
1:27:26
1:27:26
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:27:26
Jan Jansen (Birmingham, USA) & Marion Campbell (Aberdeen) present the results of the UK-REBOA trial, investigating the use of REBOA in trauma patients with severe non-compressible torso haemorrhage. The editorial is delivered by John Holcomb (also from Birmingham, USA) and the session is chaired by Catriona Kelly from Dublin. The panel discussing t…
…
continue reading
1
CRYOSTAT-2 Trial Presentation
1:30:58
1:30:58
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:30:58
Profs Nikki Curry (Oxford) and Karim Brohi (London) present the results of the CRYOSTAT-2 trial, evaluated early & empiric high-dose cryoprecipitate in patients with major traumatic haemorrhage. The editorial is delivered by Susan Rowell (Chicago) and the session is chaired by Phil Gillen from Belfast. The panel discussing the trial are Russell Gru…
…
continue reading
Prof Ivor Douglas (Denver, USA) presents the CLOVERS trial, comparing an early restrictive fluid strategy with an early liberal fluid strategy in adult patients with sepsis-induced hypotension. Prof Fernando Zampieri (Edmonton, Canada), delivers an editorial. The session is chaired by Dr Paul Mouncey (London, England).…
…
continue reading
1
PATCH-Trauma Trial Presentation
1:24:24
1:24:24
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:24:24
Russell Gruen, Brian Burns and Stephen Bernard present the results of the PATCH-Trauma trial, investigating tranexamic acid in severe trauma. An independent editorial is delivered by Karim Brohi (London). Caroline Leech (Coventry) chairs a panel discussion consisting of Susan Rowell (Chicago), Carol Hodgson (Melbourne), John Holcomb (Birmingham, US…
…
continue reading
Glenn Eastwood presents the results of the TAME cardiac arrest trial, investigating mild hypercapnoea post cardiac arrest. He is joined by senior investigators Alistair Nichol (Dublin) and Stephen Bernard (Melbourne). An independent editorial is delivered by Lars Andersen (Aarhus). Darren Taichman (Philadelphia) chairs a panel discussion consisting…
…
continue reading
Profs Matthew Prekker (Minneapolis) and Matthew Semler (Nashville) present the results of the DEVICE trial, comparing direct with video laryngoscopy for emergency intubation in the critically ill. Prof Ellen O'Sullivan (Dublin) delivers an editorial, followed by a panel discussion including Prof David Harrison (London), Dr Caroline Leech (Coventry)…
…
continue reading
Profs Giovanni Landoni and Giacomo Monti present the results of the MERCY trial, comparing bolus administration with continuous infusion of meropenem in critically ill patients with sepsis and septic shock. The results were presented at the Critical Care Reviews Meeting 2023, in Titanic Belfast. Prof Flavia Machado (Sao Paulo) delivers an editorial…
…
continue reading
1
SuDDICU Trial Presentation
1:37:24
1:37:24
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:37:24
John Myburgh and Ian Seppelt (Sydney) present the results of the SuDDICU trial at the Critical Care Reviews Meeting 2022, in Titanic Belfast. SuDDICU investigates selective digestive decontamination in critically ill mechanically ventilated patients. Naomi Hammond (Sydney) follows with a presentation of a systematic review and meta analysis also on…
…
continue reading
1
PILOT Trial Result Livestream
1:39:54
1:39:54
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:39:54
Matthew Semler presents the results of the PILOT trial, comparing low, intermediate and high oxygenation targets in critically ill mechanically ventilated patients. Paul Young delivers an editorial and Chris Nutt asks questions from the viewers. The expert panel discussion includes Victoria Cornelius, Angelique de Man, Bodil Steen Rasmussen and Gil…
…
continue reading
1
Prague Out-of-Hospital Cardiac Arrest Study
42:16
42:16
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
42:16
Prof Jan Belohlavek (Prague, Czech Republic) presents the Prague Out-of-Hospital Cardiac Arrest Study at the Critical care Reviews Meeting 2022. This study investigates the efficacy of an eCPR programme in patients with refractory out-of-hospital cardiac arrest. Dr Liz Wilcox (Toronto, Canada) follows with an editorial on the trial.…
…
continue reading
1
VAM-IHCA Trial Presentation at CCR22
40:06
40:06
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
40:06
Lars Andersen (Aarhus, Denmark) presents the VAM-IHCA trial on June 15th at the Critical Care Reviews Meeting 2022, in Titanic Belfast. The VAM-IHCA trial investigates the combination of vasopressin and methylprednisolone in in-hospital cardiac arrest. Chris Seymour (Pittsburgh, USA) delivers an editorial after the trial presentation. The session i…
…
continue reading
1
TTM2 Trial Presentation at CCR22
35:14
35:14
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
35:14
…
continue reading
1
RePHILL Trial Presentation at CCR22
54:42
54:42
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
54:42
Nick Crombie (Birmingham, England) presents the RePHILL trial, comparing pre-hospital administration of saline with blood products in patients with trauma-related haemorrhagic shock. Liz Wilcox (Toronto, Canada) delivers an editorial. The session is chaired by Catriona Kelly (Dublin, Ireland).Oleh Rob Mac Sweeney
…
continue reading
1
PREPARE II Trial Result Presentation
1:26:27
1:26:27
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:26:27
Derek Russell (Birmingham, USA) and Jon Casey (Nashville, USA) presents the results of the PREPARE II trial, investigating fluid bolus therapy for the prevention of cardiovascular collapse during emergency intubation. Anthony Gordon (London, England) delivers an editorial, which is followed by a panel discussion including Lennie Derde (Utrecht, the…
…
continue reading
1
CLASSIC Trial Results Presentation
1:25:15
1:25:15
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:25:15
Dr Tine Sylvest Meyhoff (Copenhagen, Denmark) presents the results of the CLASSIC trial at the Critical Care Reviews Meeting 2022. Prof Katryn Maitland (Kalifi, Kenya) delivers an editorial, which is followed by a panel discussion including Prof David Harrison (London, England), Dr Lennie Derde (Utrecht, the Netherlands), Dr Jon Silversides (Belfas…
…
continue reading
1
FIRST-ABC (step up) Trial Result Presentation
1:24:56
1:24:56
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:24:56
Drs Padmanabhan Ramnarayan and Paul Mouncey (both London) present the results of the FIRST-ABC trial, comparing high-flow nasal cannulae therapy with CPAP in acute ill children with respiratory failure, at the Critical Care Reviews Meeting 2022. Dr Srinivas Murthy (Vancouver) delivers an editorial, which is followed by a panel discussion including …
…
continue reading
1
NITRIC Trial - Panel Discussion
40:04
40:04
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
40:04
Rob Mac Sweeney (Belfast, Northern Ireland) hosts a panel discussion including Prof Paul Checchia (Houston, USA), Prof Wes Diddle (Washington DC, USA), Prof Ranjit Lall (Coventry, England), Prof Kathy Rowan (London, England), as well as the NITRIC trial chief investigator Luregn Schlapbach (Zurich, Switzerland) and editorialist Prof Mark Peters (Lo…
…
continue reading
Dr Bronwen Connolly asks cheif investigator Luregn Schlapbach questions from the viewers during the livestream of the NITRIC trial resultsOleh Rob Mac Sweeney
…
continue reading
Prof Mark Peters, from Great Ormond Street Hospital, delivers an editorial on the NITRIC trial, investigating nitric oxide during cardiac surgery for children with congenital cardiac disease. The chief investigator for the trial Assoc Prof Luregn Schlapbach replies.Oleh Rob Mac Sweeney
…
continue reading
Assoc Prof Luregn Schlapbach (Zurich, Switzerland) presents the results of the NITRIC trial, investigating nitric oxide during cardiac surgery for children with congenital cardiac disease.Oleh Rob Mac Sweeney
…
continue reading
1
FIRST-ABC Trial Results - Panel Discussion
47:47
47:47
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
47:47
Rob Mac Sweeney hosts a panel discussion on the results of the FIRST ABC trial, comparing HFNO with CPAP in recently extubated children. The panelists are Martha A.Q. Curley (Philadelphia), Christopher M. Horvat (Pittsburgh), Martin Kneyber (Groningen), and David Harrison (London). They are joined by Padmanabhan Ramnarayan (chief investigator), Alv…
…
continue reading
1
FIRST-ABC Trial Results - Viewers' Questions
14:40
14:40
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
14:40
Chris Nutt (Belfast) asks the chief investigator of the FIRST-ABC trial Padmanabhan Ramnarayan (London) questions from the viewers during the livestream presentation of the trial results.Oleh Critical Care Reviews
…
continue reading
1
FIRST-ABC Trial Results - Editorial
13:24
13:24
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
13:24
Adrienne Randolph (Boston) delivers an independent editorial on the FIRST-ABC (Step Down) trial, comparing high flow nasal oxygen with continuous positive airway pressure in recently extubated children.Oleh Critical Care Reviews
…
continue reading
1
FIRST-ABC Trial Results Presentation
24:30
24:30
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
24:30
Dr Padmanabhan Ramnarayan (London) and Mr Alvin Richards-Belle (London) present the results of the FIRST-ABC (Step Down) trial, comparing high flow nasal oxygen with continuous positive airway pressure in recently extubated children.Oleh Critical Care reviews
…
continue reading
Pär Johansson from Copenhagen joins Rob Mac Sweeney to discuss the fascinating phase II COMBAT-COVID trial, investigating prostacyclin in intubated patients with COVID-19 and severe endotheliopathy. The trial was published in the American Journal of Respiratory and Critical Care Medicine in November 2021.…
…
continue reading
1
PLUS Trial Result Follow Up Podcast
1:00:19
1:00:19
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
1:00:19
Naomi Hammond and Simon Finfer join Rob Mac Sweeney to discuss the reaction of the critical care community to the presentation and publication of both the PLUS trial and the systematic review and meta analysis comparing balanced solutions with 0.9% saline in the critically ill.Oleh Rob Mac Sweeney
…
continue reading
Drs Brian Driver and Matt Prekker join Rob Mac Sweeney to address some of the questions and comments that arose following the presentation and publication of the BOUGIE trial, comparing the use of a stylet with that of a bougie in emergency intubation.Oleh Rob Mac Sweeney
…
continue reading
1
BOUGIE Trial Results - Panel Discussion
37:10
37:10
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
37:10
Dr Rob Mac Sweeney (Belfast, Northern Ireland) chairs a panel discussion on the results of the BOUGIE trial, comparing the use of a stylet with a bougie in 1102 patients requiring emergency intubation in either the emergency department or the ICU. The panelists are Prof Jonathan Benger (Bristol, England), Dr George Kovacs (Halifax, Canada), Dr Jean…
…
continue reading
1
BOUGIE Trial Results - Viewer's Questions
9:23
9:23
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
9:23
Dr Chris Nutt (Belfast, Northern Ireland) asks questions posed by viewers of the BOUGIE trial results presentation livestream. These are answered by Dr Matt Semler (Nashville, USA) and Dr Brian Driver (Minneapolis, USA). Prof Jonathan Benger (Bristol, England) also joins the discussion.Oleh Rob Mac Sweeney
…
continue reading
Prof Sheila Myatra (Mumbai, India) delivers an independent editorial on the BOUGIE trial, comparing the use of a stylet with a bougie in 1102 patients requiring emergency intubation in the emergency department or the ICU. Dr Matt Semler (Nashville, USA) and Dr Brian Driver (Minneapolis, USA) reply to the editorial and Prof Jonathan Benger (Bristol,…
…
continue reading
1
BOUGIE Trial Results Presentation
25:33
25:33
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
25:33
Dr Jon Casey (Nasville, USA), Dr Stacy Trent (Denver, USA) and Dr Brian Driver (Minneapolis, USA) present the results of the BOUGIE trial at a Critical Care Reviews Trial Results Livestream, on December 8th, 2021. The BOUGIE trial compared the use of a stylet with a bougie in 1102 patients requiring emergency intubation in the emergency department …
…
continue reading
Theresa Olasveengen (Oslo, Norway), Victoria Cornelius (London, England) and Christopher Seymour (Pittsburgh, USA) join trialists Mikael Fink Vallentin and Lars Andersen (Aarhus, Denmark), as well as editorialist Gavin Perkins (Coventry, England), to discuss the COCA trial.Oleh Rob Mac Sweeney
…
continue reading
1
COCA Trial - Viewer's Questions
12:00
12:00
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
12:00
Dr Chris Nutt asks Dr Mikael Fink Vallentin and Lars Andersen questions form the viewers, during the livestream presentation of the COCA trial results. The COCA trial investigates calcium for out-of-hospital cardiac arrest and was presented at a Critical Care Reviews Trial Results Presentation Livestream on November 30th, 2021, with a simultaneous …
…
continue reading
1
COCA Trial Results Presentation
29:34
29:34
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
29:34
Drs Mikael Fink Vallentin and Lars Andersen (University of Aarhus, Denmark) present the results of the COCA trial, investigating calcium for out-of-hospital cardiac arrest. The COCA trial results were presented at a Critical Care Reviews Trial Results Presentation Livestream on November 30th, 2021, with a simultaneous publication in JAMA.…
…
continue reading
Prof Gavin Perkins (University of Warwick) delivers an editorial on the COCA trial, investigating calcium for out-of-hospital cardiac arrest. The COCA trial results were presented at a Critical Care Reviews Trial Results Presentation Livestream on November 30th, 2021, with a simultaneous publication in JAMA.…
…
continue reading
1
The HOPE Trial Preliminary Results
24:44
24:44
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
24:44
Dr Bharath Kumar presents preliminary results of the HOPE trial and discusses the difficulties of undertaking research during a pandemic.Oleh Rob Mac Sweeney
…
continue reading
1
COVID STEROID 2 Trial Results Presentation - Panel Discussion
39:40
39:40
Main Kemudian
Main Kemudian
Senarai
Suka
Disukai
39:40
Bram Rochwerg (Hamilton, Canada), Paul Mouncey (London, England) & Colin McArthur (Auckland, New Zealand) join trialists Sheila Nainan Myatra (Mumbai, India), Bala Ventakesh (Brisbane, Australia) and Anders Perner (Copenhagen, Denmark), as well as editorialists Marion Campbell (Aberdeen, Scotland), to discuss the COVID STEROID 2 trial.…
…
continue reading