Conversations with scientists at the forefront of brain research. Hosted by neuroscientist Mark Mattson.
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Activists, researchers, influencers, permaculturists and entrepreneurs are coming together to participate in The Greater Reset Activation, an initiative of The Freedom Cell Network. The Greater Reset is a direct counter to the World Economic Forum's The Great Reset initiative held every January since 2021. Learn more: https://www.thegreaterreset.org
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Let's explore ideas and concepts that make designers and entrepreneurs like us tick. Join us as we feed our insatiable curiosity seeking answers to the questions relevant to our listeners from inside and outside Central Europe.
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S4:E97 – Dr. Lydia Gian. de Leon & Arturo Ponce de Leon - Architecture for Life Harmonics (The Greater Reset 5: Manifestation)
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On January 18, 2024, Dr. Lydia Gian. de Leon & Arturo Ponce de Leon spoke at The Greater Reset 5: Manifestation on Day 2, Permaculture & Food Independence. Lydia is a Greek Architect and Wellness Coach, with a focus on the relation of buildings on health and well-being. She holds a Ph.D in Physiology on the subject of the effect on geophysical anom…
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S4:E96 – Yoshi and Pola Pantera - Beyond Sustainability: The Art of Regenerative Culture (The Greater Reset 5: Manifestation)
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On January 18, 2024, Yoshi and Pola Pantera spoke at The Greater Reset 5: Manifestation on Day 2: Permaculture & Food Independence. Yoshi and Pola will unveil actionable solutions for cultivating regenerative habits, principles, and tools, drawing from ancestral wisdom. They’ll guide you in accelerating personal healing and embracing a regenerative…
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S4:E95 – Jim Gale - Together We Win! (The Greater Reset 5: Manifestation)
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On January 18, 2024, Jim Gale spoke at The Greater Reset 5: Manifestation for Day 2: Permaculture & Food Independence. Jim is an outdoor enthusiast, entrepreneur, permaculture expert, financial expert, husband, father, and friend. A 4-time All American and National Champion wrestler, Jim has excelled at pursuing his goals with fervor and passion in…
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S4:E94 – Paul and Lauren Bell - Perma-Culture: Growing Roots and Manifesting Community (The Greater Reset 5: Manifestation)
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On January 18, 2024, Paul and Lauren Bell spoke at The Greater Reset 5: Manifestation for Day 2: Permaculture & Food Independence. Paul and Lauren Bell are the founders of TruthLoveAndFreedom.com, a platform for activism, teaching Natural Law, morality, and voluntaryism, as well as BlueHillFarmOrganics.com, both of which operate from their certifie…
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S4:E93 – Sean Hawkins - The Power of Mushrooms (The Greater Reset 5: Manifestation)
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On January 18th, 2024, Sean Hawkins spoke at The Greater Reset 5, for Day 2: Permaculture & Food Independence. Sean Hawkins is a Mushroom grower, Soil Smith, teacher & student of regenerative agriculture, and citizen scientist. Owner of Cultivated Mind, a wellness based mycology & herbal focused company. We grow and source the highest quality organ…
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S4:E92 – Sarah Wu - Regenerative Herbalism (The Greater Reset 5: Manifestation)
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On January 18th, 2024, Sarah Wu spoke at The Greater Reset 5, for Day 2: Permaculture & Food Independence. Sarah Wu is a passionate educational curator, facilitator and mentor dedicated to adult learners of all backgrounds. A representative for Mother Nature as a writer and teacher of Deep Ecology, Therapeutic Ecology and Whole Systems Design share…
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S4:E91 – Kenny Palurintano - You Are What (and How) You Eat (The Greater Reset 5: Manifestation)
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On January 18th, 2024, Kenny Palurintano spoke at The Greater Reset 5, for Day 2: Permaculture & Food Independence. A lifelong anarchist, Kenny has been living out of a backpack since 2015, trust-falling the Universe every day, and starving the state in every way he can. After being a full-time content creator for more than half a decade, Kenny “re…
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David Nutt: The Drug Science – Drug Regulation Disconnect and Its Impact on Individuals and Society
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David Nutt has made major contributions to understanding mechanisms by which psychoactive drugs affect the brain and has conducted numerous clinical trials of a wide range of drugs in patients with various mental disorders. He has also been an outspoken critic of the disconnect between drug science and government drug policies. For example, alcohol…
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Yaakov Stern: Cognitive Reserve and Individual Differences in Brain Aging and Alzheimer’s Risk
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Some elderly individuals remain cognitively ‘sharp as a tack’ despite the accumulation of large amounts of amyloid in their brains, whereas others exhibit profound cognitive impairment with less amyloid pathology. In this episode Columbia University Professor Yaakov Stern talks about the concepts of ‘cognitive reserve’ and ‘brain maintenance’ and h…
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Anna Borghi: Embodied Cognition, Inner Speech, Language, and Abstract Concepts
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What are the foundational principles by which acquired information is organized and processed in the human brain? In this episode University of Rome Professor Anna Borghi talks about several prominent working theories of cognition including embodied cognition (interactions with objects and other people), inner speech, and abstract concepts. She tal…
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David Menon: Reducing the Burden of Traumatic Brain Injuries by Improving Recovery
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Traumatic brain injuries (TBI) are a major cause of long-term disability and burden on families and health care systems. University of Cambridge Professor David Menon is a leader in global efforts to better understand and treat TBI. In this episode Dr. Menon talks about what happens to neurons, glial cells, and blood vessels in the brain after a TB…
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Martin Picard: Mitochondrial Psychobiology, Neuroplasticity, Stress, and Brain Health
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Mitochondria are best known as the powerplants within cells. But recent research is revealing that mitochondria play fundamental roles in regulating the structure and function of neuronal networks and the behaviors that those networks control. Martin Picard directs the Mitochondrial Psychobiology Group at Columbia University. In this episode I talk…
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Charles Nemeroff: Understanding, Preventing, and Treating Depression in the Digital Age
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Approximately 20 percent of people in the USA will experience clinical depression during their lifetime and there has been a recent surge in depression and suicide among teenagers and young adults. The early life environment plays a major role in one’s vulnerability to depression with childhood maltreatment greatly increasing the risk. Recent resea…
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Long-Jun Wu: Microglia and Their Roles in Neuroplasticity, Chronic Pain, Brain Injury, and Disease
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Historically, microglia were viewed only as the brain’s immune cells that respond to brain injury or infections. While this is true, recent research has shown that microglia play important roles in responding to and regulating neuronal network activity, and adaptations of the brain to physiological challenges such as exercise and intellectual chall…
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Alvaro Pascual-Leone: Transcranial Magnetic Stimulation for Brain Disorders in the Digital Age
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Transcranial magnetic stimulation (TMS) is a non-invasive technology that enables stimulation (or inhibition) of specified neuronal networks in the brain. In this episode Alvaro Pascual-Leone, a Professor in Neurology at Harvard Medical School, talks about the principle and practice of TMS and its use for the treatment of a range of brain disorders…
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Dena Dubal: Longevity Factor Klotho, Cognition, Brain Aging, and Alzheimer’s Disease
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In 1997 Makoto Kuro-o and his colleagues reported that they had accidentally discovered a gene that encodes a protein that slows aging and extends the lifespan of mice. They named the protein ‘Klotho’ after the Greek goddess that ‘spins the thread of life’. During the past decade University of California San Francisco professor Dena Dubal has shown…
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Marija Kundakovic: Epigenetics, Brain Sex Differences, Environmental Factors, and Mental Health
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The brains of males and females are different and it is important to understand how these differences give rise to different behavioral traits of men an women. These sex differences arise during brain development, manifest throughout life and are controlled in part by estrogen and testosterone. The brains of females and males, and their differentia…
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S4:E90 – Hakeem Anwar - Energetics: The Future of Health (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Hakeem Anwar spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Hakeem Anwar (formerly Ramiro Romani), technologist, entrepreneur, and educator will be sharing the foundational science behind energetics, demystifying how they work and pointing to a few technologies that should be in every household. He…
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S4:E89 – Jason Christoff - Ancient Black Magic Mind Control In Our Modern Time (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Jason Christoff spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Jason Christoff breaks down some real life examples of media/government mind control in our modern time, what the primary end goals are and how to make 2024 your best year yet. Jason Christoff runs an international overcoming self sabot…
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S4:E88 – Carey Wedler - Save the World: Stop Paying Attention (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Carey Wedler spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Former independent journalist Carey Wedler explores the dark side of "waking up" and the seemingly paradoxical power of disengaging from finding "the truth" in our journeys toward consciousness and freedom. Carey Wedler is a content creato…
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S4:E87 – Miriam Gomez - Manifestation - The Process of Liberation (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Miriam Gomez spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Miriam is an artist, entrepreneur, permaculturist and activist. She started practicing meditation in 2013 and since then has now led over 150 guided group meditations through MedMob (a world flash mob meditation action network), as part of…
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S4:E86 – Luis Fernando Mises - Liberate Your SELF Through Breathwork (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Luis Fernando Mises spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Luis Fernando is the principal of Emancipated Human LLC. He has vision to be present and empower people and has been doing that for over a dozen years. He has been developing servant leadership programs for over a decade and has bee…
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S4:E85 – Antony Sammeroff - How Pharma Money Manipulates & Monopolises Institutions (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Antony Sammeroff spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Antony Sammeroff is a psychotherapist and economics journalist known for the book Universal Basic Income – For and Against. Antony has been writing on the pharmaceutical industry and the corrupt economics of healthcare for years. You c…
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S4:E84 – Iluminati Congo - Easy Psychedelic Breathing (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Illuminati Congo presented at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. Illuminati Congo is a Chicago-based one-of-a-kind project melding hip hop aesthetic with reggae consciousness, imagined and realized by visionary frontman Jahn Da Baptist and backed by production created by Nic the Graduate. The la…
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S4:E83 – Bodreay Fraser - A New Paradigm of Health and Empowerment (The Greater Reset 5: Manifestation)
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On January 17th, 2024, Bodreay Fraser spoke at The Greater Reset 5, for Day 1: Liberate Your Mind, Body, & Soul. BoDreay Fraser is the Creator of iHealCollective, a conscious health community that aims to brings together diverse practitioners from all modalities and walks of life, to offer patients a variety of healing modalities . From Ancient Tec…
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Eduard Vieta: Bipolar Disorder: Genes, Environment, and Lithium
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Bipolar disorder is a mental illness that causes often dramatic shifts in a person’s energy and activity levels, and concentration. It affects approximately 1 in every 50 people worldwide and 6 million Americans. Many people with bipolar disorder exhibit remarkable creativity and productivity. This relationship between creativity and mania was note…
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Tanya Paull: ‘AT’: How Studies of a Rare Genetic Disorder Advanced Neuroscience and Cancer Research
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Ataxia Telangiectasia (AT) is a rare inherited disorder in which young children develop severe ataxia (inability to control body movements) as a result of degenration of ‘Purkinje neurons’ in the cerebellum. AT children are highly prone to cancers and usually die before the age of 20. In this episode Professor Tanya Paull talks about research that …
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Bandy Lee: Case Study USA: A Combustible Mixture of Psychopathic Behavior, Power, Divisiveness, and Violence
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In this episode I talk with Dr. Bondy Lee, a psychiatrist who has devoted her life to advancing an understanding the causes of violence and developing ways to reduce violence. As a psychiatrist she is particularly interested in the behavioral features of people who are a danger to society, particularly those with psychopathic traits and behaviors s…
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S4:E82 – Announcing The Evolution of The Greater Reset!
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Derrick Broze, co-founder of The Greater Reset Activation, shares his thoughts on The Greater Reset 5: Manifestation in Morelia, Mexico, and shares what's next for the solutions-focused movement known as The Greater Reset. Learn more about The Greater Reset: https://thegreaterreset.org Watch The Greater Reset Activation 1-5: https://odysee.com/@The…
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Thomas Sudhof: Molecular Codes for Synapse Formation and Specificity
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In this episode I talk with Stanford Professor and Nobel laureate Thomas Sudhof about his work that has advanced an understanding of the molecular machinery for neurotransmitter release, a remarkable process that is compex, occurs rapidly (milliseconds) and is highly localized (1 micrometer or less). We then talk about the even more difficult probl…
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Christiane Wrann: How Exercise Enhances Brain Neuroplasticity and Resilience
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Regular exercise improves mood, reduces anxiety, enhances cognition, and protects the brain against depression, Alzheimer’s disease and stroke. In this episode Harvard neuroscientist Christiane Wrann and I talk about recent research that has elucidated how exercise affects the structure, functionality, and resilience of the brain. The mechanisms in…
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William Seeley: Frontotemporal Dementias and Selective Neuronal Vulnerability
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Frontotemporal dementia (FTD) is the most common form of dementia for people under the age of 65. As its name implies FTD involves degeneration of neurons in the frontal and parietal lobes and depending upon which neurons degenerate symptoms may mainly involve changes in personality and social behavior, speech and language (aphasia), or difficulty …
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Russell van Gelder: Emerging Technologies for Vision Restoration
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Age-related macular degeneration, glaucoma, diabetic retinopathy, and genetic disorders such as retinitis pigmentosa are major causes of blindness. In this episode Professor Russ van Gelder at the University of Washington talks about exciting advances in vision restoration using retinal cell replacement, gene therapy, visual prosthetic devices, and…
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Sergiu Pasca – Human Neuroassembloids: Building Brains in the Laboratory
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The molecular and cellular mechanisms by which the human brain develops cannot be directly studied. Stanford professor Sergiu Pasca is at the forefront of using induced human pluripotent stem cells to establish 3D cultures of individual brain regions (organoids) and multiple interacting brain regions (assembloids). His work has shown that functiona…
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Mayowa Owolabi: Strategies for Reducing Global Burden of Stroke and Other Neurological Disorders
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Stroke is the leading neurological cause of disability and death throughout the world and is increasing on the African continent where rates of hypertension are high and Westernized dietary habits are on the rise. At the forefront of the global battle against stroke and other age-related neurological disorders is Mayowa Owolabi, Dean of the Faculty…
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S4:E81 – The Freedom Cell Network presents The Greater Reset 5: Manifestation
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Join us in Morelia, Mexico from January 17-21, 2024 as we create the better world we know is possible! Tune in online for FREE or attend in person to witness more than 40 presenters and performers sharing solutions in the areas of mental, physical, & spiritual health; Permaculture & Food Independence; Parallel Systems; Decentralized Tech; and Build…
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George Perry: Oxidative Stress and Synaptic Dysfunction in Alzheimer’s Disease
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Because neurons are very active cells they consume high amounts of oxygen and produce high amounts of oxygen free radicals (oxyradicals). Because most neurons in the brain exist throughout life and cannot be replaced it is critical that they be able to efficiently remove oxyradicals and repair damage caused to DNA, proteins and membranes caused by …
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Li-Huei Tsai: Gamma Frequency Light and Sound Stimulation for Alzheimer’s Disease
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There is currently no effective treatment for Alzheimer’s disease. EEG recordings have shown that gamma frequency electrical oscillations are diminished and aberrant excitatory glutamatergic neurotransmission is increased in the brain’s of people with Alzheimer’s disease. In this episode MIT Professor Li-Huei Tsai talks about her discovery that gam…
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Vilhelm (Will) Bohr: DNA Damage and Repair, Brain Aging, and Alzheimer’s Disease
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DNA damage, most often caused by oxygen free radicals, can result in mutations in proliferative cells that transform them into cancer cells. Impaired DNA repair is implicated in aging and neurodegenerative disorders. In this episode Professor Will Bohr talks about his research on the molecular mechanisms by which cells repair their nuclear and mito…
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Gabriele Saretzki: Beyond Telomeres: Telomerase in Neuroplasticity and Neurodegenerative Disorders
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The ends of chromosomes are called telomeres. In dividing cells a reverse transcriptase called telomerase adds a six-base DNA repeat to the telomeres thereby preventing their shortening. Telomere shortening occurs in proliferative tissues during aging and has been associated with a range of diseases. This led to the dogma that the only function of …
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Gyorgy Buzsaki: Brain Rhythms, Neural Syntax, and the Emergence of Cognition from Action
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NYU professor Gyorgy Buzsaki has made seminal contributions to understanding how neuronal networks in the brain encode and processes information. He established the synaptic basis of the brain’s theta and gamma rhythms, and sharp waves. Based upon extensive amounts of data generated from multielectrode recordings he developed a two-stage model of m…
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Thiruma Arumugam: Intermittent Fasting, Neuroplasticity and Neuroprotection
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In this episode I talk with professor Thiruma Arumugam of Latrobe University about research on the effects of intermittent fasting on brain health and vulnerability to disorders such as stroke, Alzheimer’s and Parkinson’s diseases. This research was prompted by evidence that daily caloric restriction with time-restricted feeding, and every other da…
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David Rubinsztein: Autophagy 2.0: An Anecdote for Poisonous Proteins in Neurodegenerative Disorders
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Accumulation of toxic proteins in neurons that wither and die is a fundamental problem in neurodegenerative disorders - Alzheimer’s disease, Parkinson’s disease, Frontotemporal dementia, ALS, and Huntington’s disease. In this episode Professor David Rubinsztein at the University of Cambridge talks about how impaired autophagy results in the accumul…
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Stephen Morse: ‘NeuroLaw’ - Neuroscience and Criminal Law
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The facts that all human behaviors are controlled by the brain and that all crimes involve behaviors beg the question of if and how advances in neuroscience might improve the criminal justice system. Professor Stephen Morse at the University of Pennsylvania Law School and Center for Neuroscience and Society on problems of individual responsibility …
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David Rubinsztein: Autophagy 1 – How Cells Dispose of Molecular Trash
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Even as the carry out their usual functions molecular components of cells are damaged by oxygen free radicals and other processes. Cells remove such cellular trash by moving it into ‘acid baths’ called lysosomes in a process called autophagy. Research during the past 30 years has revealed the molecular mechanisms of autophagy and have provided evid…
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Edward Calabrese: The Hormesis Revolution in Biology, Neuroscience, and Medicine
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Professor Ed Calabrese has spent much of his life pouring over tens of thousands of dose – response data from studies in fields ranging from toxicology and radiation biology to cancer, neuroscience, and aging. His work has firmly established the hormesis principle as foundational for evolution and health. In the fields of biology and medicine horme…
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Rich Ivry: The Cerebellum’s Roles in Timing, Error Correction, and Cognition
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Inconspicuously tucked under the cerebral cortex at the back of the brain the cerebellum was long believed to only function as a controller of smooth and accurate body movements. During the past 40 years professor Rich Ivry at the University of California Berkeley has made major contributions to research that has revealed a much more complex repert…
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Dirk de Ridder: Brain and Spinal Cord Stimulation Therapies for Chronic Pain, Tinnitus, etc.
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Chronic pain affects more than 20 percent of people and is the leading cause of disability and loss of productivity. Recent development in technologies and protocols for electrical non-invasive or invasive stimulation or inhibition of specific pathways in the brain or spinal cord are being developed. At the forefront of this area of neurology is Di…
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Tamas Horvath: Hunger, Energy Metabolism, Mitochondria, and Anorexia
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The discomforting feeling of hunger evolved to motivate searching for food and is therefore critical for survival. However, for modern-day humans living in environments where food is continuously available excessive hunger can result in obesity. In this episode Yale University professor Tamas Horvath talks about ‘hunger neurons’ in the hypothalamus…
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Wolf Singer: Solving the Hard Problem of Consciousness
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In this episode of Brain Ponderings I talk with the German neuroscientist Wolf Singer about the hard problem of consciousness and how it might be solved. Wolf is a Professor at the Max Planck Institute of Brain Research and the Institute for Advanced Studies in Frankfurt Germany. Perhaps more than anyone else in the world Wolf has elucidated how ne…
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