Podcast terbaik Professor Declan Murphy (2024)

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Ten Years of ENZAMET | the gift that keeps on giving! 40:48

1d ago40:48

40:48

Today we celebrate one of our favourite clinical trials - ENZAMET! It is 10 years since ENZAMET opened and beyond its pivotal data establishing that adding enzalutamide to ADT improves survival for mHSPC patients, it continues to produce a very strong stream of high-quality findings that affect our practice today. ENZAMET also straddled an epochal …

1
All your GU Highlights from #ESMO24! 54:00

5d ago54:00

54:00

Ask anyone which big oncology meeting gave us the best GU oncology highlights this year and the answer is easy! ESMO24 in Barcelona! Jammed full of key papers and so many highlights, Declan and Renu bring you a great overview in this GU Cast Conference Highlights from ESMO24. Listen to discussions with investigators and key opinion leaders, intervi…

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GU Cast vs The Penis Project! With Melissa Hadley-Barrett 26:45

17d ago26:45

26:45

Penis Project is one of our favourite podcasts (and certainly popular with our patients), so we were delighted to welcome Host and Sexologist, Melissa Hadley-Barrett to join us for a chat. What is the Penis Project? Who is it for? (anyone with a penis, anyone who knows someone with a penis, or anyone who would like to have a penis apparently)! A cr…

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Spectacular live robotic surgery at #ERUS24 in Bordeaux 1:05:13

21d ago1:05:13

1:05:13

The world's longest running live robotic surgery meeting took place in Bordeaux last week and Declan and Renu were there to bring you all the highlights! The 21st Meeting of the EAU Robotic Urology Section (ERUS) was their biggest ever with more than 1000 delegates watching more than 40 live surgeries from the world's top robotic surgeons. And this…

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LuPSMA moves UpFront | first RCT data with Arun Azad and Michael Hofman 34:38

27d ago34:38

34:38

A big day at ESMO in Barcelona today as our friend and colleague A/Professor Arun Azad presents the results of the UpFront PSMA trial for the first time. The data were revealed in the main prostate cancer session at ESMO and simultaneously published in Lancet Oncology. UpFront PSMA is a randomised controlled trial comparing ADT and docetaxel, with …

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Salvage Robotic Radical Prostatectomy | 500 cases later with Paul Cathcart 30:52

1M ago30:52

30:52

More than 500 salvage radical prostatectomies!!! Yep it would be fair enough to describe Dr Paul Cathcart as being "experienced" in the most challenging scenario we face as prostate cancer surgeons. Surgery for cancer recurrence in the prostate following radiotherapy or various forms of ablative therapy is never easy, and can all too often lead to …

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Three Big Waves in Testis Cancer | With Rob Hamilton and Ben Tran 26:14

1M ago26:14

26:14

Testis cancer! We don't talk enough about this on GU Cast. But we are making up for it today with a cracking overview of three hot topics in testis cancer a couple of world-leading testis cancer experts. We are joined by Rob Hamilton (Urologist, Princess Margaret Cancer Centre, Toronto), and Ben Tran (Medical Oncologist, Peter Mac, Melbourne) to di…

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Why you should go to Bali!! | #UAA24 7:10

1M ago7:10

7:10

As if any of us need an excuse to go to beautiful Bali! Well the Urological Association of Asia (UAA) Annual Meeting takes place there from 5-8th September 2024. Renu caught up with Dr Agus Rizal Hamid recently to hear what the UAA have in store for us! www.uaa2024.comOleh Professor Declan Murphy & Dr Renu Eapen

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PSA and Testosterone | Why low numbers matter 20:37

2M ago20:37

20:37

How often do you check PSA and testosterone in your patients on androgen deprivation therapy? Probably not often enough!! Declan caught up with friend of the podcast Professor Axel Merseburger at a conference recently to chat about this under-appreciated topic. Don't get too distracted by fancy scans and genomic testing; but do make sure you know a…

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Remembering Dr Brian Kelly 1:30:47

2M ago1:30:47

1:30:47

Today we dedicate our podcast to the memory of our colleague, Dr Brian Kelly (40), who passed away unexpectedly this week. We are devastated to lose Brian, who was a Consultant Urologist at Peter Mac and Eastern Health here in Melbourne, and one of our closest friends in the world. Here we replay the Memorial Session which we conducted at Peter Mac…

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Three big things in advanced/high risk kidney cancer | With Rana McKay and Lewis Au 38:20

2M ago38:20

38:20

We were very happy to have world-famous kidney cancer guru Dr Rana McKay in Australia this week to do some educational events and to visit us at Peter Mac. So of course we also invited her to the GU Cast studio to pick her brains on all things kidney cancer, along with Dr Lewis Au, GU Medical Oncologist at Peter Mac. We asked them to cover three ho…

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Sunshine and Science from #ANZUP24 on the Gold Coast 52:19

2M ago52:19

52:19

Renu and Declan escape winter in Melbourne to enjoy a few days of sunshine and science at the #ANZUP24 Annual Scientific Meeting on the Gold Coast. ANZUP is our fantastic GU Oncology co-operative trials group here in Australia and New Zealand and have an outstanding record in running clinical trials and supporting research and education in GU Oncol…

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The Prostate Cancer Olympics 2024! With Elena Castro and Arun Azad 44:13

3M ago44:13

44:13

To celebrate the Paris 2024 Olympics, we bring you this special Olympics-themed episode of GU Cast - our very own Prostate Cancer Olympics! Yes we We are joined in the GU Cast studio by Dr Elena Castro, GU Medical Oncologist at Hospital 12 de Octubre in Madrid, who happened to be passing through Melbourne. And by our own A/Professor Arun Azad, GU M…

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Radical prostatectomy and the wave of new robots in China today 33:15

3M ago33:15

33:15

In the second of our special episodes focussing on GU Oncology in China, we are delighted to welcome back our GU Cast China Editor. Professor Yao Zhu, who has put together this cracking epsiode focussing on radical prostatectomy in China. We are joined by Professor Ming Liu (Beijing Hospital, Beijing) and Professor Jiahua Pan (Ren Ji Hospital, Shan…

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We meet the Active Surveillor | Howard Wolinsky 36:08

3M ago36:08

36:08

There are patient advocates and there are patient advocates, and then there is Howard Wolinsky! We chat with the inimitable Howard, medical journalist and very long-time active surveillance patient, about his varied interests in low-risk prostate cancer and prostate cancer diagnostics. He runs a great substack called The Active Surveillor with a re…

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#APCCC24 Conference Highlights | Part 2 1:06:10

3M ago1:06:10

1:06:10

Part 2 of our Conference Highlight specials from the Advanced Prostate Cancer Consensus Conference, held in April 2024 in Lugano. This is our very favourite prostate cancer meeting and we are thrilled to bring you these highlight podcasts. In this episode we chat with Elena Castro, Nick James, Anthony Joshua, Bertrand Tombal, Silke Gillessen, Aurel…

1
2024 EAU Prostate Cancer Guidelines - some big changes!! 47:52

4M ago47:52

47:52

Pelvic lymph node dissection down-graded. Systematic prostate biopsies no longer recommended. More clarity around PSMA PET/CT for staging. Surgery no longer recommended for cN1 prostate cancer. Yep the recent updates to the EAU Prostate Cancer Guidelines had a lot of important changes for the global urology community to digest. So we invited EAU Pr…

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#APCCC24 Conference Highlights | Part 1 49:26

4M ago49:26

49:26

The first of two Conference Highlight specials from the Advanced Prostate Cancer Consensus Conference, held in April 2024 in Lugano. This is our very favourite prostate cancer meeting and we are thrilled to bring you these highlight podcasts. In this epsiode we chat with Silke Gillessen, Derya Tilki, Jochen Walz, Neha Vapiwala, Dingwei Ye, and the …

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GU Highlights at #ASCO24 | with Marty Schoen 35:00

4M ago35:00

35:00

Didn't get to ASCO this year?? Us neither!! But not to worry, we checked in with Dr Marty Schoen who did, and brings us all the key highlights! Marty is a GU Medical Oncologist at the St Louis Veterans Affairs Medical Centre and the University of St Louis, Missouri. He runs through a smattering of stuff that caught his eye at ASCO this year. Thanks…

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Pembro improves survival after nephrectomy | Huge news for Urologists 45:57

4M ago45:57

45:57

For Urologists, there are not that many papers that come along where we can say - "this will almost immediately change my practice". But KEYNOTE-564 looks like one of those! A large phase III randomised trial of adjuvant pembro following nephrectomy for renal cell carcinoma in patients deemed at higher risk for recurrence. Regular listeners/viewers…

1
En-bloc party! RCT of TURBT with Jeremy Teoh 29:46

5M ago29:46

29:46

Should we remove bladder cancers piece-meal by chopping them into little pieces, or should we try and remove en bloc with a margin around the base?? This very nice randomised controlled trial from our friends in Hong Kong demonstrates that the recurrence rate is significantly lower if we use the all-too-rarely used en bloc technique. Dr Jeremy Teoh…

1
Three big challenges in metastatic prostate cancer | Dr Alicia Morgans 38:04

5M ago38:04

38:04

Today we have Dr Alicia Morgans, GU Medical Oncologist and Director of Survivorship at Dana Farber Cancer Institute, in the GU Cast studio for a chat. We wanted to ask Alicia to look forward and identify three big challenges we will face in metastatic prostate cancer over the next 5-10 years. What did we come up with??!! Tune in to find out!! Even …

1
Metastatic prostate cancer in China today 40:48

5M ago40:48

40:48

In the first of our special episodes focussing on GU Oncology in China, we are delighted to welcome our inaugural GU Cast China Editor. Professor Yao Zhu, to the GU Cast studio. Yao is a Urologist at Fudan University Shanghai Cancer Centre, and is well known to all of us at GU Cast and Peter MacCallum Cancer Centre. As part of our Gold Partnership …

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Uro-Podcasters Love-in in Lugano!! 16:50

6M ago16:50

16:50

Great fun on the shores of Lake Lugano where the hosts of three of the best -known podcasts in GU Oncology get together for a chat! Declan and Renu from GU Cast, join with Brian and Tom from Uromigos, and Gill from Oncoalert. How did it all start? Why did it all start?! Best moments, worst moments etc. Tune if for a chat, and do please subscribe/li…

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ProsTIC24 PSMA Theranostics Conference Highlights 47:21

6M ago47:21

47:21

The 2nd ProsTIC Preceptorship is one of the most intense fora for the discussion of PSMA theranostics anywhere in the world! A biennial meeting in Melbourne with many of the world's leading experts in the field. Not just superb practical advice about how to get your prostate cancer theranostics program to the next level, but some amazing discussion…

1
Proton therapy no better than standard prostate radiotherapy 29:57

6M ago29:57

29:57

A new paper in the Journal of Clinical Oncology is reporting that the bowel and urinary side-effects of proton therapy (a high tech and very expensive type of radiotherapy), are no better than side-effects after standard high-quality radiotherapy (called IMRT). Quite a fuss on twitter when this paper came on line last week including from a fair few…

1
ADT and cardiac risks (and how I sold my company for $1.4bn) 32:03

6M ago32:03

32:03

Professor Neil Fleshner (University of Toronto) drops into the GU Cast studio in Melbourne for an intriguing discussion! First we cover off the underrated topic of cardiac risks in patients starting androgen deprivation therapy and how we can reduce these for the benefit of our patients. Then we talk to Neil about entrepreneurship and his journey i…

1
Happy days for metastatic bladder cancer | Enrique Grande and Andrew Weickhardt 32:23

7M ago32:23

32:23

A big medical oncology love-in in the GU Cast studio today!! Professor Enrique Grande was visiting from MD Anderson Cancer Centre in Madrid to chat all about some of the sensational advances we have seen in metastatic bladder cancer in recent times. And we were also joined by old friend Professor Andrew Weickhardt from Austin Health in Melbourne to…

1
High risk prostate cancer and mHSPC | With Axel Merseburger 26:48

7M ago26:48

26:48

Axel Merseburger (Chief and Professor of Urology, Lubeck, Germany) was in Australia recently and popped into the GU Cast studio for a chat. Axel was at the USANZ ASM recently and also on a speaker tour supported by Janssen Pharmaceuticals, so we put together this Themed Podcast to pick his brains on high-risk prostate cancer and mHSPC in 2024. This…

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#USANZ24 Conference Highlights 59:47

7M ago59:47

59:47

Declan and Renu bring you lots of highlights and interviews from the Urological Society of Australia & New Zealand (USANZ) Annual Scientific Meeting (ASM) which took place last week in Adelaide. Almost 1000 delegates descended on this beautiful part of the world, famous for its beaches and wineries. Hear from Robert Nam, Paul Anderson, Nathan Lawre…

1
What does a randomised trial tell us about prostate biopsy? 32:22

8M ago32:22

32:22

Needle through the rectum or needle through the skin?? Transrectal vs transperienal prostate biopsy is certainly a hot topic in prostate cancer, with the vast majority of men having their biopsy through the rectum rather than through the skin. It is quick, cheap and easy (for the urologist and the health system), but leaves the patient at risk of s…

1
"Unethical trials", or so says Vinay! 49:34

8M ago49:34

49:34

Two of the highest profile presentations at the recent ASCO GU Meeting were the plenary presentations of the CONTACT 02 trial, and the Keynote-564 trial. Generally speaking, these were well received; indeed quite enthusiastically received in some quarters! Not however in the quarter of prolific oncology commentator and Haematologist/Oncologist & Pr…

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Renu's ASCO GU Highlights 54:46

8M ago54:46

54:46

Renu caught up with lots of experts and friends at ASCO GU in San Francisco recently and brings you all the highlights. Hear from Toni Choueiri, Matt Cooperberg (on that debate on renaming low-grade prostate cancer), Todd Morgan, Neha Vapiwala, Morgan Roupret, Sophia Kamran, Morgan Roupret, Sam Washington, plus a great chat with Tyler Seibert while…

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Bringing LuPSMA earlier | ProsTIC/PCF/ICIS Global Webinar 1:23:00

8M ago1:23:00

1:23:00

For all you enthusiasts of PSMA theranostics, we bring you another one of our fabulous ProsTIC/Prostate Cancer Foundation Global Webinars with some of the best minds in the business. This is the eighth of our collaborative webinars over the past four years and the focus today is bringing lutetium PSMA earlier in prostate cancer. Two keynote lecture…

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A Touchy Subject | With Victoria Cullen 44:12

8M ago44:12

44:12

A must listen (actually a must WATCH!!) episode of GU Cast if you have any experience with the side-effects of treatment of prostate cancer. Whether you are a patient or loved one, or a surgeon/radiation oncologist/medical oncologist, or a nurse or allied health professional - then this is for you. Declan and Renu chat about "A Touchy Subject" with…

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APCCC Travel Award Winners Revealed!! 3:11

8M ago3:11

3:11

We reveal the three winners of our APCCC Travel Awards 2024! These three trainees will be heading off to Lugano for the world's best prostate cancer meeting which takes place from 25-27 April on the shores of Lake Lugano.Oleh Professor Declan Murphy & Dr Renu Eapen

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Reducing "useless" lymph node dissections with PSMA 45:11

9M ago45:11

45:11

Oleh Professor Declan Murphy & Dr Renu Eapen

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Last few days to enter our great APCCC Lugano giveaway!!! 1:24

9M ago1:24

1:24

A quick message from Renu and Declan about our huge travel award giveaway to start the new year! Closing date Monday 15th Jan 2024 Full details on https://www.gucast.org/Oleh Professor Declan Murphy & Dr Renu Eapen

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Toni's Top 10 GU Oncology Papers 2023!! 39:44

9M ago39:44

39:44

A truly great Christmas tradition is when Toni Choueiri and his merry band of GU Oncology Fellows at Dana Farber, drop their list of the Top 10 GU Oncology papers of the year. And true to form, Toni's tweet on Christmas Day contains an immaculate list of GU highlights of 2023. A great mixture of tumour types, some brave choices with a Phase 1 study…

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Christmas Special | Plus our big APCCC Giveaway! 34:12

10M ago34:12

34:12

Our final podcast of 2023 and it's a big one!! Huge festive giveaway with three fully funded GU Cast travel awards to attend the APCCC in Lugano (April 2024) up for grabs. Alastair Lamb zooms in from Oxford to discuss prostate cancer spatial transcriptomics. Kiaran O'Malley (Mater Hospital, Dublin) drops into studio for a festive drink, and GU Cast…

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Lymph node dissection!! In GU Oncology 32:01

10M ago32:01

32:01

Dr Ashish Kamat (MD Anderson Cancer Centre, Houston), joins Declan and Renu to discuss a very nice paper recently published in European Urology Oncology overviewsing the role of lymph node dissection (LND) in GU oncology. Really nice piece of work led by Dr Amanda Myers along with a bunch of well known names in urologic oncology. A very succinct su…

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ARPIs for dummies! Plus the Jiffy Stent 34:16

11M ago34:16

34:16

It has becoming a familiar refrain around the world , and is certainly good news for the prostate cancer community! This week, another androgen receptor pathway inhibitor (ARPI) became reimbursed for men with hormone-sensitive metastatic prostate cancer (mHSPC) in Australia. Darolutamide is already available for men with non-metastatic castration-r…

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Lymph node recurrence - what to do and when??! With Piet Ost, Shankar Siva and Michael Hofman 30:11

11M ago30:11

30:11

SABR supremos Piet Ost and Shankar Siva join us to discuss the management of lymph node-only recurrence following primary treatment of prostate cancer. And of course our resident PSMA PET/CT guru Michael Hofman also turned up as himself and Piet love debating the merits of PSMA! How and when shoudl we image for biochemical recurrence? What are the …

1
nmCRPC made easy!! Who, when and how 37:25

11M ago37:25

37:25

Prof Fred Saad (University of Montreal) drops in to chat about the interesting condition that is non-metastatic castration-resistant prostate cancer (nmCRPC). Which men are at risk of developing metastases? When should we use an AR pathway inhibitor? Why PSMA PET/CT should NOT be used. And hear his thoughts on "dabbling" in prostate cancer! Also jo…

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Big prostate cancer highlights from #ESMO23 38:07

11M ago38:07

38:07

What a great ESMO for GU Oncology!! Declan caught up with some plenary speakers in Madrid to discuss the biggest topics. PSMA theranostics with Louise Emmett (ENZA-P) and Oliver Sartor (PSMAfore); ARPIs in biochemical recurrence with Steve Freedland (EMBARK), Morgan Roupret and Boris Hadaschik. Plus the latest negative immunotherapy trials in prost…

1
LuTectomy in European Urology 44:50

12M ago44:50

44:50

The LuTectomy trial has just been published in European Urology, and as the GU Cast team have been very much involved, we thought we should dive into the details on today's podcast. LuTectomy is a clinical trial to evaluate the role of 177-Lutetium-PSMA prior to radical prostatectomy. Declan is the study co-PI along with Professor Michael Hofman, a…

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More Shark Patting | With Tim Baker 48:26

12M ago48:26

48:26

One of our most popular episodes in 2022 was "Patting the Hormone Therapy Shark" with author, surfer and prostate cancer survivor, Tim Baker. And a lot has happened in the 12 months since so we invited Tim back for a follow-up chat in this Themed Podcast supported by our GU Cast Gold Partners, Mundipharma. Tim's inspiring approach to managing the s…

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Three big questions in high-risk prostate cancer | With Boris and Tyler 50:01

12M ago50:01

50:01

We hijacked our good friends Professor Boris Hadaschik (Urologist, Essen, Germany), and Associate Professor Tyler Seibert (Radiation Oncologist, University of California, San Diego), who happened to be in Melbourne this week, and diverted them into the GU Cast studio for a chat about high-risk prostate cancer. Boris and Tyler were on a speaker tour…

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Going Nuclear at EANM in Vienna 28:37

1y ago28:37

28:37

The European Association of Nuclear Medicine (EANM) Annual Meeting is the World's leading nuclear medicine extravaganza! Today we cross live to Professor Michael Hofman and friends to hear some of the GU highlights at this year's annual meeting in Vienna. Michael is joined by Prof Ken Herrmann, Dr Kerry Jewell, Dr Francesco Ceci, Dr Phiilip Kuo, Dr…

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Are female surgeons better than men??! 41:51

1y ago41:51

41:51

The mass media were quick to pick up on two papers in JAMA Surgery last week with headlines such as "Patients have better outcomes with female surgeons", and "Should you pick the sex of your surgeon?". So what's it all about?? We chat with lead author of one of these papers. Dr Chris Wallis, Urologist at the University of Toronto, whose looked at o…

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