TWiV 1181: Seek and ye shall find, coronaviruses and phage

This Week in Virology

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All About Change

1
Chris Nowinski - Protecting Athletes from Head Injuries & Preventing CTE 27:28

4 days ago27:28

Main Kemudian

Senarai

Suka

Disukai

27:28

Chris Nowinski is a former football player at Harvard University and professional wrestler with WWE, World Wrestling Entertainment. After enduring a career-ending head injury, Chris has dedicated his professional life to serving patients and families affected by brain trauma, particularly Chronic traumatic encephalopathy, or CTE, a progressive neurodegenerative disease that develops after repeated head injuries. Jay and Chris discuss the state of head injuries in American athletics, the difference between advocating for head safety at youth and professional levels, Chris’ newest research, and much more. Episode Chapters (00:00) Intro (00:50) changes in the culture around concussions in the past two decades (02:39) padded helmet technology (03:55) concussion reporting in the NFL (10:35) Chris’ career path and concussion history (14:52) connecting with activists who haven’t themselves suffered a traumatic brain injury (17:42) SHAAKE - a new sign to identify concussions (20:53) Unions can help players advocate for safety policies (23:10) final thoughts and goodbye For video episodes, watch on www.youtube.com/@therudermanfamilyfoundation Stay in touch: X: @JayRuderman | @RudermanFdn LinkedIn: Jay Ruderman | Ruderman Family Foundation Instagram: All About Change Podcast | Ruderman Family Foundation To learn more about the podcast, visit https://allaboutchangepodcast.com/…

about a year ago 1:52:45

MP3•Laman utama episod

TWiV discusses an outbreak of influenza H5N1 that killed over half of the great cats at a Washington sanctuary, origin and cross-species transmission of bat coronaviruses in China, and the diverse and abundant phages that enter cells via receptors encoded on conjugative plasmids.

Hosts: Vincent Racaniello, Rich Condit, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
H5N1 virus kills great cats at Washington sanctuary (CNN)
Macroevolution of bat coronaviruses in China (Nat Comm)
EcoHealth Alliance funding suspended (Science)
Conjugative plasmids support diverse and abundant phages (Nat Comm)
Letters read on TWiV 1181
Timestamps by Jolene. Thanks!

Weekly Picks

Rich – Pareidolia (wiki) Jolene – Pathways to Science database Vincent – Wendy Carlos and Switched-On Bach

Listener Picks

Arjan – Gutsick Gibbon’s YouTube channel Alan – 2024 Nobel Prize Lectures in Chemistry

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

1223 episod

#Science #Biology #Natural Sciences #Vincent Racaniello #Disease #Infectious #Microbiology #Viral #Virology #Infection #Viruses

TWiV 1181: Seek and ye shall find, coronaviruses and phage

This Week in Virology

84 subscribers

published about a year ago

Kongsi

MP3•Laman utama episod

Hosts: Vincent Racaniello, Rich Condit, and Jolene Ramsey

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

Support science education at MicrobeTV
ASV 2025
H5N1 virus kills great cats at Washington sanctuary (CNN)
Macroevolution of bat coronaviruses in China (Nat Comm)
EcoHealth Alliance funding suspended (Science)
Conjugative plasmids support diverse and abundant phages (Nat Comm)
Letters read on TWiV 1181
Timestamps by Jolene. Thanks!

Weekly Picks

Rich – Pareidolia (wiki) Jolene – Pathways to Science database Vincent – Wendy Carlos and Switched-On Bach

Listener Picks

Arjan – Gutsick Gibbon’s YouTube channel Alan – 2024 Nobel Prize Lectures in Chemistry

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.

1223 episod

#Science #Biology #Natural Sciences #Vincent Racaniello #Disease #Infectious #Microbiology #Viral #Virology #Infection #Viruses

Semua episod

This Week in Virology

1
TWiV 1197: The long and short of influenza 1:40:57

5 days ago1:40:57

1:40:57

TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Ann Palmenberg dies (Cress) Ann at Chumakov Symposium (YouTube) Unknown illness in Congo (NY Times) Bad news about mpox outbreak (NPR) US interrupts Ebola prevention program (NPR) First measles death in Texas (Texas Trib) Flu vaccine selection meeting canceled (NY Times) US ends funding for polio, HIV, malaria and more (NY Times) Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio) Predictors of durable antibody responses to vaccines (Nat Immunol) Review of adjuvants (Vaccinol Methods Vacc Res) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Video of the Northern Lights from Space Rich – Vaccination for Sudan Ebola virus disease Alan – Specialized moth wing scales give it 3-D camouflage ( news and paper ) Vincent – WHO Recommendations for Influenza Vaccine Composition for the 2025-2026 Northern Hemisphere Influenza Season Listener Picks Gerry – Eukaryotic Transcription Anne – The science of the solar system Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1196: Clinical update with Dr. Daniel Griffin 58:53

6 days ago58:53

58:53

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from “postponement” of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the ‘flu vaccine’ before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and growing measles outbreak in the US including misinformation from the Secretary of HHS, highly pathogenic avian flu and its economic effect, ie the cost of eggs before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions and FDA approval of adjuvanted Novovax COVID vaccine. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Phantom ACIP (CDC) Postponement of ACIP…..hummmm (STATNews) Influenza Strain selection VRBPAC cancelled (Reuters) How NIH funded research is impacted by government communication pause (NY Times) Can be reviewed but still no money (STATNews) Final push to end Ebola in Uganda (WHO Uganda) Saudi Arabia sponsors polio eradication effort (GPEI)) $500 million from Saudi Arabia to immunize 370 million children against polio (CIDRAP) Measles 124 in Texas …. (Texas Health and Human Services) A Texas child who was not vaccinated has died of measles(AP News) The Measles book-(Apple Books) Measles vaccination protects against virus infection and other infections (Science) Measles deadliest sequelae (MEDPAGE TODAY) Measles cases and outbreaks (CDC Measles) Unvaccinated Child Dies of Measles in Texas Outbreak(NY Times) Texas child is first reported US measles death in a decade as outbreak hits more than 130 (Reuters) Trump’s cabinet meeting : Kennedy Shocker “Not unusual”……..seriously! (YouTube) First measles death reported in Texas as Kennedy downplays the outbreak (NBC News) Measles cliff notes : symptoms timeline (Substackdn) Annual state immunization report (Texas Health and Human Services) Measles imported into Kentucky …….no tariffs? (Commonwealth of Kentucky) Egg shortage affect flu shots? (MEDPAGE TODAY) Which Came First , the Chicken Slaughter or the Egg Shortage(Wall Street Journal) Avian Influenza in Birds: Causes and How It Spreads (CDC Avian Influenza) Agriculture Secretary Brooke Rollins: My Plan to Lower Egg Prices (Wall Street Journal) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) US respiratory virus activity (CDC Respiratory Illnesses) Trump administration yanks CDC flu vaccine campaign(NPR) RSV- Net work (CDC Respiratory Syncytial virus Infection) New wild to mild campaign drives key message to tame flu and reset expectations (CDC Influenza) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Effectiveness of the original monovalent messenger RNA Coronavirus Disease 2019 (COVID-19) vaccination series against hospitalization for COVID-19–Associated venous thromboembolism (JID) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Demographic variation in US outpatient hydroxychloroquine and ivermectin use during the COVID-19 pandemic (HealthAffairs) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Alleviation of COVID-19 symptoms and reduction in healthcare utilization among high-risk patients treated With nirmatrelvir/ritonavir (NMV/R) (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Interventions for Long COVID: A Narrative Review (Journal of General Internal Medicine) COVID-19 vaccination and odds of post–COVID-19 condition symptoms in children aged 5 to 17 Years (JAMA Network) Novavax COVID-19 vaccine , adjuvanted (FDA) Letters read on TWiV 1196 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1195: Dickson Despommier, parasitologist without borders 1:51:32

11 days ago1:51:32

1:51:32

The entire TWiV team comes together to pay tribute to Dickson Despommier, then reviews antibodies to H5N1 virus in veterinarians working with dairy cattle, Elisabeth Bik donates prize money for data integrity analyses, measles outbreak in Texas, and use of an alternative genetic code by human microbiome phages. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , Brianne Barker , Daniel Griffin , Angela Mingarelli, and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Livestream tribute to Dickson (Office Hours) Dickson’s Wikipedia page Dickson’s obituary (NY Times) Dickson websites: trichinella.org , thelivingriver.org , fordhamopolis.com , despommierphotoart.com Alan’s tribute to Dickson (alandove.com) H5N1 seroprevalence (MMWR) Elisabeth Bik donates prize money (Science) Measles outbreak in Texas (Texas DSHS) Human microbiome phages use alternative genetic code (Nat Comm) Letters (mostly not) read on TWiV 1195 – all about Dickson Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Rare spotting of humpback anglerfish “diablo negro” ( Melanocetus johnsonii) in Tenerife, Canary Islands. First time ever observed alive! Brianne – Moonwalking with Einstein inspired by reading NY Times article about Recent memory champ Kathy – Witness History 9 minute podcasts Rich – APOD: Perijove 11: Passing Jupiter Alan – Ecological succession on abandoned farmland Jolene – Parasitic Diseases Lectures and first 27 episodes of This Week in Parasitism Vincent – The New City Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1194: Clinical update with Dr. Daniel Griffin 58:58

13 days ago58:58

58:58

In his weekly clinical update, Dr. Griffin and Vincent Racaniello reminiscence about Dickson before discussing discharging Ebola patients, another announcement of emergency measures to control polio spread and the third nOPV2 vaccination campaign in Gaza in less than 6 months, the measles outbreak in the US, vaccination campaign for chickens against high pathogenic avian flu before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode In memory of Dickson (NY Times) All Ebola patients discharged in Uganda (DG Alerts) Uganda discharges Ebola patients (WHO Uganda) Emergency measures to stop polio…..isn’t this the same plan as last year? (GPEI)) A third nOPV2 campaign…..but I thought OPV stops transmission (Reuters) Worst outbreak of measles in 30 years for Texas…. go big or go home ! (AP News) Measles 58 in Texas …. (Texas Health and Human Services) High pathogenic avain influenza virus infection of indoor domestic cats (CDC MMWR) Avian influenza in dairy cattle in Arizona (AZEIN) Third avian flu spillover! (CIDRAP) No vaccine hesitancy in chickens …..vaccinate all! (Science) Zoetis to supply conditionally licensed avian influenza H5N1 vaccine for chickens (Zoetis) High path avian influenza in mammals (USDA: Animal and plant health inspection service) How to vaccinate your chicken (WikiHow) Vaccine failure due to poor administration.(the poultry site) Human cases of H5N1 in US rise to 4 (CBS News) Canada’s buying vaccine as US rats become infected (CIDRP) Canada purchases avian influenza vaccine for those at high risk (Canada Public Health) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) How the communications pause endangered us about influenza (AP News) Most intense flu season in 15 years (AP News) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) RSV- Net work (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) COVID-19 case fatality rate and infection fatality rate from 2020 to 2023 (Journal of Infection and public health) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in healthy volunteers (eBioMedicine) Ensitrelvir for the Treatment of Nonhospitalized Adults with COVID-19 (CID) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Letters read on TWiV 1194 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1193: HPV or not to B 1:43:00

19 days ago1:43:00

1:43:00

TWiV reviews a facility accident that killed monkeys, new bird blu genotype found in Nevada dairy cattle, Argentina plans to leave WHO, yellow fever on the rise, dynamics of HPV infections in women, and Epstein-Barr virus protein targets B cell receptor for degradation. Hosts: Vincent Racaniello , Alan Dove , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Accident kills monkeys at SC research supply facility (Science) D1.1 Genotype in Dairy Cattle in Nevada (APHIS) Argentina to leave WHO (CIDRAP) Yellow fever on the rise (CIDRAP) HPV dynamics in women (PLoS Biol) EBV protein degrades B cell receptor (PNAS) Letters read on TWiV 1193 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Mitochondrial swap from cancer to immune cells thwarts anti-tumour defences ( one , two ) Alan – A little adventure game Vincent – The Staggering Success of Vaccines Listener Picks John – Percy Lavon Julian Debi – Don’t Look Up Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1192: Clinical update with Dr. Daniel Griffin 44:19

20 days ago44:19

44:19

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how long COVID varies between children and adults and if viral infection reduces telomere length in sperm. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Confirmation of RFK, Jr as HHS sect (NY Times) Did you know mpox in NY ?….(Reuters) Mpox in sex workers in the Congo and in NY (CIDRAP) 9 confirmed, 265 suspected Ebola cases in Uganda (AP news) WHAT!? Support vaccines : availability and development. WHAT? (Businesswire) Measles rising in the unvaccinated . You mean the vaccines does something positive? (ABC News) Measles in Texas ….go big or go home (Texas Health and Human Services) Vaccination Conscientious exemptions in Texas (Texas Health and Human Services) 2, 6, 14 measles hospitalizations in Texas (CNN) Decreases in childhood vaccinations SchoolVaxView(CDC) 2 when 24 cases of measles in two weeks (Texas Health and Human Services) Measles in small town Texas (NY Times) Measles in the US Texas , Georgia , Rhode Island, New York, New Mexico: Elimination of measles (JID) Influenza taxonomy (NCBI) H5N9 in commercial duck farm, California (American Animal Hospital Association) Second type of bird flu circulating in ducks (Scientific Amercia) Variant H1N2 flu in Iowa (CIDRAP) All types of influenza (CDC Influenza) Bird flu in the zoos : Bronx and Queens (Gothamist) High path avian influenza in mammals (USDA: Animal and plant health inspection service) Bird flu in house cats …..I tawt I taw a puddy tat (KFF Health News) New strain of influenza in dairy cows (AP News) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) How the communications pause endangered us about influenza (AP News) Most intense flu season in 15 years (AP News)US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Weekly US influenza surveillance report (CDC FluView) RSV- Net work (CDC Respiratory Syncytial virus Infection) 10 year surveillance of RSV hospitalization in adults(JID) Seasonality of RSV: 2017-2023(CDC: MMWR) What doctors wish patients know about RSV (AMA) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Proportion of Long COVID incidence in adults and children (CID) SARS-CoV-2 infection effects sperm telomere length (Journal of Assisted Reproduction and Genetics) Pediatric gastrointestinal tract outcomes during the postacute phase of COVID-19c]\ (JAMA Network) Letters read on TWiV 1192 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv…

This Week in Virology

1
TWiV 1191: The pandemic duo 1:44:43

26 days ago1:44:43

1:44:43

TWiV reviews freezes and unfreezes of US government grants, how prior COVID-19 vaccination prevents over-reaction of the innate immune response during infections, and how bat genomes illuminate adaptations to viral tolerance and disease resistance. Hosts: Vincent Racaniello and Alan Dove Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 NIH freezes (ScienceAdviser) Is your research on Trump’s hit list ? (ScienceInsider) Prior COVID-19 vaccination tames innate responses (Sci Transl Med) Bat genomes illuminate viral tolerance and disease resistance (Nature) Letters read on TWiV 1191 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Alan – NOAA Space Weather Prediction Center dashboards Vincent – He created a hummingbird paradise in his backyard Listener Picks Christiane – Contact your members of Congress about the Pause in Federal Grant Funding Charles – What’s trending in the world of pseudoscience Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1190: Clinical update with Dr. Daniel Griffin 46:46

27 days ago46:46

46:46

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association of vaccine associated paralytic poliomyelitis before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, an update of Paxlovid administration provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, how children may be affected by long COVID and if SARS-CoV-2 and other inflammatory syndromes increase the risk of Alzheimer’s disease. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode The return of MMWR (CDC) Largest tuberculosis outbreak ever in the US (Kansas Department of Health and Environment) Marburg virus outbreak in Tanzania (Doctors without borders) No USAID, Ebola outbreak in Uganda spreads (CBS News) WHO accelerates efforts to Ebola response in Uganda (WHO: Uganda) Global partners enable access to vaccine and treatment for Ebola outbreak in Uganda (WHO) Ventilation and respiratory viruses (CDC National Institute for Occupational safety and health) Is bird flu flying through the air …..is the virus literally airborne? (NY Times) Is bird flu like measles (American Journal of Epidemiology) Indoor safety guideline (Herokuapp) Dairy herds in Nevada have influenza! (CIDRAP) Do your eggs have H5N1? (NY Times) New genotye D1.1 of avian flu in dairy cattle(USDA Animal and Plant Health Inspection Service) Second spillover of avian flu into dairy cattle….does this story sound familiar? (CIDRAP) Impact of using nOPV2 in mass vaccination campaigns? (JID) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) As flu increases so do deaths in kids (CIDRAP) People most impacted by respiratory viruses (CDC) Co-infection with SARS-CoV-2 and influenza A/B (BMC Infectious Diseases) Oseltamivir reduces 30-Day mortality in older adults with Influenza (OFID) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV- Net work (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Paxlovid update (Pfizer) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID Recovery Program with Zara Dureno, BA, MOT Long COVID pevalence and associated activity limitation in US children (JAMA Pediatrics) Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection (Nature Medicine) Letters read on TWiV 1190 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv…

This Week in Virology

1
TWiV 1189: Viruses making waves 1:32:45

5 weeks ago1:32:45

1:32:45

TWiV notes the HHS communication pause, and describes research showing that rotavirus viroporin activity is necessary for intracellular calcium signals that contribute to viral pathogenesis, and control of human orthrflavivirus vaccine challenge by T cells in the absence of neutralizing antibodies. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Rotavirus viroporin activity, calcium waves , and pathogenesis (Sci Adv) T cells control human orthoflavivirus challenge (Nat Micro) Letters read on TWiV 1189 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – The Perfect Cacio e Pepe Recipe, According to Science (primary article here ) Kathy – Dragonflies Loop-the-Loop Alan – My Beloved Monster , by Caleb Carr Vincent – Why Did the FDA Ban Red Dye #3 Listener Picks Anne – Japan’s 65-Foot Towering Snow Walls Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1188: Clinical update with Dr. Daniel Griffin 47:49

5 weeks ago47:49

47:49

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information, the Marburg and Ebola outbreaks in Africa, the largest tuberculosis outbreak in the US ever, the politicization of polio vaccine campaigns in Pakistan, effect of high pathogenic influenza in animals and on the economy before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, trials and devices to relieve some neurological complications of long COVID and the ramifications of long COVID in children, healthcare workers and adults. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode No morbidity and mortality in the US this week? (NPR) More support for Marburg outbreak in Tanzania (Reliefweb) Tanzania confirming second Marburg case (CIDRAP) Norovirus mRNA vaccine …..hmmmm? (moderna) What is noronvirus? (modernatx) Largest tuberculosis outbreak ever in the US (Reuters) Ebola outbreak in DRC during US:WHO strain (STAT News) Uganda Ebola outbreak…..1 dead (Reuters) Polio outside endemic zone due to militants? (Washington Post) Mpox vaccination initiation in central Africa (CIDRAP) Preparing rapid response to emerging infectious disease in Africa (PANTHER Health) Mpox therapeutic study MOSA enrollment begins (Africa CDC) Halting of US foreign aid for health programs…..not in the US best interests? (NY Times) No PEPFAR (NY Times) PEPFAR (US Department of State) PEPFAR…..still not America first? Really? (CIDRAP) Resurgence of infections globally may affect US…..what is global health? (NY Times) Milk testing for H5N1….but I thought raw milk was the only healthy milk? (USDA) How do you like your $10.99 dozen of eggs? (NY Times) Farm outbreak of H5N1 (AP News) US- high pathogenicity avian influenza viruses (World Organization for Animal Health) H5N9 high pathogenic flu in duck farm California (CIDRAP) More egg issues (CIDRAP) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV- Net work (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory syncytial virus vaccine effectiveness among US veterans, September, 2023 to March, 2024 (LANCET Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID Recovery Program with Zara Dureno, BA, MOT The current and future burden of long COVID in the United States (JID) Transcutaneous vagus nerve stimulation improves Long COVID symptoms in a female cohort (Frontiers in Neurology) Transcutaneous vagus nerve stimulation trials: https://www.mountsinai.org/clinical-trials/tvns-in-long-covid-19 https://www.centerwatch.com/clinical-trials/listings/NCT06585254/tvns-in-long-covid-19 Devices: https://pulsetto.tech/products/meet-pulsetto?pulsetto_offer_id=57&transaction_id=1024e5a0258b6647e262ba8fec5d62 https://www.dolphinmps.com/product/dolphin-neurostim-professional-single-kit-vagal-stim-kit/ Distinct pro-inflammatory/pro-angiogenetic signatures distinguish children with Long COVID from controls (Pediatric Research) Persistent symptoms and clinical findings in adults with post-acute sequelae of COVID-19/post-COVID-19 syndrome in the second year after acute infection(PLoS Medicine) SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York (LANCET: Regional Health Americas) Impact of COVID-19 Pandemic on the incidence and prevalence of postural orthostatic tachycardia syndrome (EHJ-QCCO European Heart Journal-Quality of Care & Clinical Outcomes) Letters read on TWiV 1188 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv…

This Week in Virology

1
TWiV 1187: The tau of herpesvirus 1:56:41

6 weeks ago1:56:41

1:56:41

TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer’s disease. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , Brianne Barker , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Entry receptor for EV-D68 (Cell Host Microbe) Anti-herpetic tau preserves neurons in Alzheimers (Cell Rep) Letters read on TWiV 1187 Timestamps by Jolene Ramsey. Thanks! Weekly Picks Angela – Good genes are nice, but joy is better Brianne – Beaker Hair Clip Kathy – Pareidolia explained by street artist David Zinn TEDx talk Also visit zinnart.com Alan – Screwworm is coming back in the Americas Vincent – Dr. Jay Bhattacharya Was Nice to Someone During a Debate. That Doesn’t Erase the Consequences of His Misinformation Listener Picks Sarah – The Extremophile Campaign: In Your Home (ECIYH) citizen science Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1186: Clinical update with Dr. Daniel Griffin 46:59

6 weeks ago46:59

46:59

In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, and where to go for answers to your long COVID questions. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Tanzania confirms Marburg virus outbreak (Reuters) Clade Ib mpox in England (Reuters) Withdrawing from the World Health Organization (WhiteHouse) Fees costs behind withdrawing from WHO ….is that what we are suppose to believe? (Sky News) Sorry to see you go , US? (WHO) Where are the updates ? (CDC Health Alert Network) Pause in health communications of all kind (Washington Post) NIH chaos…..streaming to a halt? (STAT News) Devastation at the NIH, hiring traveling, meetings, communications(Science) Protect your cat from bird flu (NPR) No communication and cats with bird flu ….does not sound good (CIDRAP) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Baloxavir marboxil for prophylatix against influenza(NEJM) Comparative effectiveness of baloxavir marboxil and oseltamir treatment for reducint household transmission of influenza (Influenza and other respiratory viruses) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV- Net work (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) Host-microbe multiomic profiling identifies distinct COVD-19 immune dysregulation in solid organ transplant recipients (Nature Communications) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Real‐world effectiveness and safety of oral azvudine versus nirmatrelvir‒ritonavir (Paxlovid) in hospitalized patients with COVID-19 (Signal Transduction and Targeted Therapy) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID Recovery Program with Zara Dureno, BA, MOT Letters read on TWiV 1186 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene Ramsey . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv…

This Week in Virology

1
TWiV 1185: The birds and the Bs 1:51:58

7 weeks ago1:51:58

1:51:58

TWiV explains Guillain-Barré Syndrome associated with RSV vaccines, outbreaks of metapneumovirus in China and India, editors resign to protest Elsevier’s use of AI in publishing, global distribution and diversity of wild bird associated pathogens, and broadly inhibitory anti-neuraminidase antibody from human memory B cells. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 GBS with RSV vaccine (FDA) Increase in respiratory infections in China (ECDC) Elsevier journal editors resign (Retract Watch) Wild bird associated pathogens (Med) Broad anti-neuraminidase antibody (Cell Host Micr) Letters read on TWiV 1185 Timestamps by Jolene . Thanks! Weekly Picks Brianne – Dear Reviewer 2 Rich – National Data Buoy Center Alan – BBC audio program on the World Morse Code Championships Vincent – These are the 20 most-studied bacteria — the majority have been ignored Listener Picks Peter – Local graffiti in Sydney Vivian – The Peoples’ Hospital by Dr. Ricardo Nuila Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

This Week in Virology

1
TWiV 1184: Clinical update with Dr. Daniel Griffin 45:46

7 weeks ago45:46

45:46

In his weekly clinical update, Dr. Griffin discusses current and past outbreaks of “vaccine” preventable diseases including whooping cough, polio and measles with your co-host Vincent Racaniello and the recent increase in norovirus outbreaks, if alcohol-based hand sanitizers aid in the spread of norovirus before reviewing the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, if “long COVID” like symptoms occurs after influenza and how long COVID may associate with neurological complicates that control verbal memory. Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Notable infectious diseases in US (CDC NNDSS) Get your Tdap : whooping cough case increase (California Department of Public Health) Resurgence of measles among preschool aged children 1989-1991 (CDC: MMWR) Adults vulnerable to ‘childhood’ diseases (NY Times) Pivotal decision that led to a resurgence of polio (NY Times) Can polio return due to lagging vaccination ? (NY Times) NoroSTAT Data Table (CDC Norovirus) The discovery of the 27-nm Norwalk virus : an historic perspective (JID) Why the “ Ferrari of viruses ” is surging through the northern hemisphere (Science) Waste water scan for 11 pathogens (WastewaterSCan) Norovirus at Chipotle, $25million food fine (NY Times) Chipotle food issues: 2015 settlement with the justice department (Chipotle News) Purcel anyone? Hand sanitizers increase norovirus risk? (Canadian Medical Association Journal) Visualization by immune electron microscopy of a 27nm particle associated with acute infectious nonbacterial gastroenteritis (Journal of Virology) Winter vomiting disease (JID) ACIP: expanded recommendations for pneumococcal conjugate vaccines(CDC: MMWR) Presumptive bird flu case in San Francisco (SF. Gov) Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Antiviral medications for treatment of nonsevere influenza(JAMA Network: JAMA Internal Medicine) Xofluza (GoodRx) RSV: Waste water scan for 11 pathogens (WastewaterSCan) RSV- Net work (CDC Respiratory Syncytial virus Infection) US respiratory virus activity (CDC Respiratory Illnesses) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Fusion center near you….if in NY (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society) Drug interaction checker (University of Liverpool) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC) Managing healthcare staffing shortages (CDC) Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org) Daniel Griffin’s evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) Symptom evolution in individuals with ongoing symptomatic COVID-19 and post COVID-19 syndrome after SARS-CoV-2 vaccination versus influenza vccination (Journal of Infection) Neurological post-COVID syndrome is associated with substantial impairment of verbal short-term and working memory (Scientific Reports) Letters read on TWiV 1184 Dr. Griffin’s COVID treatment summary ( pdf ) Timestamps by Jolene . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv…

This Week in Virology

1
TWiV 1183: More than 2024 viruses 1:49:31

8 weeks ago1:49:31

1:49:31

TWiV reviews some of their favorite virology stories from 2024. Hosts: Vincent Racaniello , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 SARS-CoV-2 origins ( TWiV Special ) TWiV 1163: Hepadnaviridae in the heartland TWiV 1117 Pol dances with the RNA that brought it HPV vaccine success (TWiV 1083 , 1151 , 1159 , 1173 ) Monkeypox (TWiV 1095 , 1119 , 1143 , 1145 , 1147 ) Influenza H5N1 virus (V TWiV 1113 , TWiV 1131 , TWiV 1173 ) Influenza B/Yamagata removed from vaccine ( TWiV 1161 ) Fiasco of poliomylelitis eradication ( TWiV 1091 , TWiV 1125 , TWiV 1105 , TWiV 1151 , TWiV 1145 , TWiV 1147 , TWiV 1161 , TWiV 1143 ) Protective immunity isn’t just bout antibodies (TWiV 1089 , 1105 , 1115 , 1135 , 1165 ) Closing the toilet lid doesn’t help ( TWiV 1083 ) Timestamps by Jolene . Thanks! Weekly Picks Brianne – Scientists put vampire bats on treadmills to learn about metabolism Kathy – Says Who?: A Kinder, Funner, Usage Guide for Everyone Who Cares About Words Rich – Mark Rober on PBS Newshour Brief But Spectacular ( Wiki ; Testing The World’s Smartest Crow ) Vincent – How Glenn Gould Broke Classical Music Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.…

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