Technologies Based on Lanthanides Emissions to Perform Ultrasensitive Assays | Innovative New Technologies with Roger Bosse, Ph.D. (Sponsored by TheWell Bioscience)

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This week we welcome the President of BioSignal2, Inc Roger Bossé, Ph.D., to discuss using technologies based on Lanthanides emission (TRF, TR-FRET, LOCI) to perform ultrasensitive assays. Bosse is a leading expert on a wide range of detection technologies and applications that work in conjunction with microplate readers.

Key Learning Points:

• What lanthanides are and how they can be used for assays
• The type of research lanthanide-based assays are ideal for
• What researchers need to know to use lanthanide-based assays for research
• The future advancement of lanthanide-based assays technology

Learn more about our BioSignal2 Inc. by visiting: http://www.biosignal2.com/

About Roger Bosse:
Bosse was the key individual that commercialized and developed the unique screening reagent platform “AlphaScreen” at PerkinElmer. He then expanded its breadth and scope to cover many applications in drug discovery and life sciences in general. Roger is highly skilled at assay design and development for early drug discovery efforts and has extensive cell signaling expertise.

Our Sponsor for this Episode
TheWell Bioscience – developer of VitroGel, a next-generation xeno-free 3D extracellular matrix (ECM), enables scientists to shift from 2D to 3D cell culture and help drive innovations for precision medicine, cell therapy and biomanufacturing by getting faster and more accurate data than animal-based systems.
Learn more about TheWell Bioscience by visiting:
www.thewellbio.com
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About SLAS
SLAS (Society for Laboratory Automation and Screening) is an international professional society of academic, industry and government life sciences researchers and the developers and providers of laboratory automation technology. The SLAS mission is to bring together researchers in academia, industry and government to advance life sciences discovery and technology via education, knowledge exchange and global community building. For more information about SLAS, visit www.slas.org.

SLAS publishes two peer-reviewed and MEDLINE-indexed scientific journals, SLAS Discovery and SLAS Technology. For more information about SLAS and its jour

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Bab

1. Our Sponsor: TheWell Bioscience (00:00:00)

2. Introduction (00:00:53)

3. What makes the metals fluorescent (00:04:01)

4. How to manipulate lanthanides (00:06:03)

5. What got Roger interested in lanthanides (00:07:44)

6. What research problems does this technology solve (00:08:28)

7. How are assays visualized? (00:09:43)

8. What does the speed of activation tell researchers (00:11:30)

9. What types of research are lanthanides ideal for (00:11:57)

10. How difficult is it to learn how to use lanthanides (00:18:21)

11. Are there any major disadvantages of using this technology? (00:20:36)

12. Other uses (00:20:37)

13. What researchers need to know to start using lanthanides (00:22:33)

14. Future Advances for this technology (00:24:41)

15. Wrap up (00:26:06)