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18. In-depth analysis of negative controls: using Nobel Laureates’ as example (mini-series: reading-11)

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Kandungan disediakan oleh Dr. Synaptologica. Semua kandungan podcast termasuk episod, grafik dan perihalan podcast dimuat naik dan disediakan terus oleh Dr. Synaptologica atau rakan kongsi platform podcast mereka. Jika anda percaya seseorang menggunakan karya berhak cipta anda tanpa kebenaran anda, anda boleh mengikuti proses yang digariskan di sini https://ms.player.fm/legal.

Today's focus: negative controls. In life-science experiments, negative controls play critical roles. In my view, they are more important than the positive controls! They form such a rich topic that we will spend at least a few episodes on discussing them. Today, we introduce basic aspects: 1) what the negative controls do in life-science experiments, 2) our practical definition by modifying the typical and ideal one, 3) how the negative control was used in our milestone graph (Fig. 3D of milestone article 1 by the Laureates of the Nobel Prize in Physiology or Medicine 2023), and 4) two critical assumptions for negative controls to work properly.
This is Part 11 of the reading mini-series "Let’s read a paper written by Nobel Prize Laureates, 2023."
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20 episod

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Manage episode 409865497 series 3493940
Kandungan disediakan oleh Dr. Synaptologica. Semua kandungan podcast termasuk episod, grafik dan perihalan podcast dimuat naik dan disediakan terus oleh Dr. Synaptologica atau rakan kongsi platform podcast mereka. Jika anda percaya seseorang menggunakan karya berhak cipta anda tanpa kebenaran anda, anda boleh mengikuti proses yang digariskan di sini https://ms.player.fm/legal.

Today's focus: negative controls. In life-science experiments, negative controls play critical roles. In my view, they are more important than the positive controls! They form such a rich topic that we will spend at least a few episodes on discussing them. Today, we introduce basic aspects: 1) what the negative controls do in life-science experiments, 2) our practical definition by modifying the typical and ideal one, 3) how the negative control was used in our milestone graph (Fig. 3D of milestone article 1 by the Laureates of the Nobel Prize in Physiology or Medicine 2023), and 4) two critical assumptions for negative controls to work properly.
This is Part 11 of the reading mini-series "Let’s read a paper written by Nobel Prize Laureates, 2023."
(My email is active. But my website is under construction. Please wait for a while. Thank you for the patience!)

  continue reading

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