“Crime Junkie" host Ashley Flowers and Rob are talking true crime! Ashley joins Rob Lowe to talk about their shared love for Indiana, the cases they are obsessed with, Ashley’s dream of making a cameo on “Law & Order: SVU,” naming her company after her beloved dog, why they both adore Caitlin Clark, her new show "Crime Junkie AF" on her SiriusXM ch…

Ted and Woody are back together to bring you a brand new podcast from Team Coco! It’s called “Where Everybody Knows Your Name with Ted Danson and Woody Harrelson (Sometimes)" and it’s out right now! They’re talking to guests like Conan O’Brien, Will Arnett, Jane Fonda, Billy Eichner, Kristen Bell, and yours truly! I got to join Ted for an episode a…

At long last, Rob’s son Matthew Lowe is on the show! VC investor, attorney, and fisherman Matthew Lowe joins Rob to discuss golfing with his mom Sheryl Lowe in Hawaii, appearing in “The West Wing” as a kid, watching Dad’s movies as a family, encouraging his father to join “Parks & Rec,” sitting next to Rob in the iconic NFL hat photo, studying for …

Wildlife biologist and outdoor adventurer Forrest Galante joins Rob Lowe to discuss re-discovering animals thought to be extinct, his recent “Shark Week” shoots, the real-life story that inspired “Jaws”, Rob’s recent experience getting stung by a stingray, and much more. Plus, Rob shares his thoughts on the Roast of Tom Brady and his suggestions fo…

Adam and Rob remember the days of woodshop class! Comedian and podcaster Adam Carolla joins Rob Lowe to discuss the odd jobs he did before entering show business, his unconventional first encounter with longtime friend Jimmy Kimmel, betting big on podcasting back in 2009, listening to “Loveline” as a teenager, the value of woodshop class, and his n…

When Rob has questions about the future of technology and artificial intelligence, he goes to Marc Andreessen! Legendary investor and entrepreneur Marc Andreessen joins Rob Lowe to discuss the future of TikTok in the U.S., three major ways that artificial intelligence will improve the lives of everyday people, how a simple photo landed Kenny G in a…

Things get very silly when Thomas and Rob are together. Actor, writer, and comedian Thomas Lennon joins Rob Lowe to discuss the new Netflix film “Unfrosted,” receiving notes from Jerry Seinfeld, Thomas and Rob's ridiculous on-set jokes from the filming of “Monster Trucks,” getting fired gracefully, how studio lot parking spaces reveal your true sta…

Jeff and Rob both love performing drama AND comedy! Jeff Daniels joins Rob Lowe to discuss how working with Jim Carrey on “Dumb and Dumber” taught him fearlessness, committing to his thick accent in Netflix’s “A Man in Full,” his memories of the brilliant James Gandolfini, their experiences performing Aaron Sorkin dialogue, watching Shirley MacLain…

Rob is entering his 60s and committing to a better diet…with the help of the esteemed Dr. Mark Hyman! Dr. Mark Hyman (renowned physician, medical advisor to the Clintons, and the host of “The Doctor's Farmacy” podcast) joins Rob Lowe to discuss the Ozempic revolution, the real key to longevity, the obesity statistic that shocked Rob, what foods to …

Comedian, actor, and podcaster Paul Scheer joins Rob Lowe to discuss celebrity-owned restaurants, the “M*A*S*H” theme song, why the team behind “The League” decided to end the show while they were still on top, Rob’s traumatic childhood talent show memory, the greatest audition story ever, and Paul’s new memoir, “Joyful Recollections of Trauma.” Pr…

Kelly Ripa joins Rob Lowe to discuss getting “knighted” by Disney, the joys of working with her husband, why Rob was one of Kelly’s favorite guest co-hosts, trying out the Oculus headset, Rob’s 60th birthday party, her podcast “Let's Talk Off Camera with Kelly Ripa,” and her big goal to get out of hair and makeup! Got a question for Rob? Call our v…

Katey and Rob looooove talking to other sober people! Actress and musician Katey Sagal joins Rob Lowe to discuss her new podcast with husband Kurt Sutter, the joys of sobriety, the passing of her godfather Norman Lear, being a Keith Richards girl, working with the amazing John Ritter, why “Sons of Anarchy” convinced Rob to go buy a biker jacket, be…

Tig and Rob are silent laughers. Comedian Tig Notaro joins Rob Lowe to discuss their shared obsession with the song “Do They Know It’s Christmas?” by Band Aid, her foolproof method for testing potential TV show titles, her love for drama and despair, her podcast “Handsome,” and her new comedy special, “Hello Again.” Plus, Rob reveals a bit of White…

Rob is a huge admirer of the incredible activist and R&B musician Daryl Davis. He is the first Black author to write a book on the Ku Klux Klan (KKK) based on in-person interviews, and he has convinced dozens of Klansmen to leave and denounce the hate group. Today, Daryl joins Rob to discuss his incredible activism work, the power of conversation, …

Rob Lowe and Ted Sarandos love to quote their favorite movies together! Co-CEO of Netflix (and film fanatic) Ted Sarandos joins Rob Lowe to discuss his early days as a video store manager in Arizona, the little-seen Netflix comedy series that he is obsessed with, how the Netflix algorithm and his own fandom led to the company’s deal with Adam Sandl…

This episode of “Literally” is unlike any other. Rob Lowe is joined by Nando Parrado, one of the 16 survivors of the Uruguayan Air Force Flight 571, which crashed in the Andes mountains in 1972. After spending 72 days trapped in the mountains, Nando, along with his friend and teammate, climbed through the Andes mountains for 10 days to find help. N…

Hilary and Rob go waaaaaaaay back! Hilary Swank joins Rob Lowe to discuss her baby twins, being called “too half-hour” by a CBS executive, the photoshoot she did for Rob and Sheryl in the 90’s, the incredible animal rescue work Hilary did in the wake of 9/11, skiing with Clint Eastwood, memories from the Oscars, and why she feels her father would b…

Jon and Rob have been in the same circles for decades, but now they are finally getting some quality time together! Jon Cryer joins Rob Lowe to discuss the Brat Pack days, auditioning for "St. Elmo's Fire," the surprising connection between Jon’s mom and Rob’s mom, working with Charlie Sheen on "Two and a Half Men," and Jon’s new sitcom, "Extended …

Rob and Rev Run are kindred spirits! The legendary rapper, DJ, and minister Rev Run joins Rob Lowe to discuss the incredible legacy of his group Run-DMC, growing up in the sixties and seventies, focusing on family, finding inspiration in the tub, and the new Peacock docuseries, "Kings From Queens: The Run DMC Story.” Got a question for Rob? Call ou…

Cheryl and Rob have so much to catch up on! Cheryl Hines joins Rob Lowe to discuss the final season of “Curb Your Enthusiasm,” Larry David’s run-in with Elmo, how she would dress as First Lady, choosing your Secret Service code-name, Cheryl’s mom’s birthday at Thunder Down Under, and much more. Got a question for Rob? Call our voicemail at (323) 57…

In honor of her 70th birthday, Rob is looking back at his 2021 conversation with the amazing Oprah Winfrey! The two friends discuss what it means to live in gratitude, the wisdom of Toni Morrison, meeting your heroes, and so much more. Got a question for Rob? Call our voicemail at (323) 570-4551. Your question could get featured on the show!…

Rob and filmmaker Ed Zwick have so many great memories from shooting their 1986 film “About Last Night!” Filmmaker Ed Zwick (creator of “thirtysomething” and director of “The Last Samurai” and “Legends of the Fall”) joins Rob to revisit “About Last Night,” and discuss Ed’s work with Tom Cruise, the death of a certain kind of adult drama film, advic…

Rob wouldn't mind swapping lives with Hollywood legend Brian Grazer for a day! The prolific film and TV producer (whose credits include “24,” “Arrested Development,” “Apollo 13,” and “A Beautiful Mind”) joins Rob to discuss the future of Hollywood, how to revamp the Oscars ceremony, the differing worldviews of “The West Wing” and “24,” his book on …

It’s a love-fest when old friends Robert Downey Jr. and Rob Lowe get together! Rob is talking to his former high school classmate and longtime friend: the great Robert Downey Jr. Hear them discuss their shared memories from Santa Monica High School, surviving the 1980s, the genius of Christopher Nolan, and growing from set-backs. Robert’s latest fi…

Ted Danson and Rob Lowe have watched the entertainment industry transform! Ted Danson joins Rob Lowe to discuss the incredible legacy of “Cheers,” the optimistic comedy of “The Good Place” and “Parks & Recreation,” his experiences working with Steven Spielberg and Larry David, learning that his show was canceled while touring the Sistine Chapel, an…