On The Bioinformatics CRO Podcast, we sit down with scientists to discuss interesting topics across biomedical research and to explore what made them who they are today.
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Tony Altar - neuropharmacology and advice for young scientists
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Tony Altar, President and COO of Splice Therapeutics, returns to The Bioinformatics CRO Podcast to discuss the present and future of neuropharmacology, skateboarding, and how to make the most of your health and career. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnolog…
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Mo Jain - novel technologies for biomarker discovery
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Mo Jain, Founder and CEO of Sapient, discusses the importance of small molecule biomarkers and his approach to biomarker discovery research. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Evan Floden - Nextflow and Reproducibility in Science
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Evan Floden, CEO and Co-founder of Seqera Labs, discusses Nextflow, the push for reproducibility in scientific workflows, and his experience as a scientist with a start-up. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https:/…
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Linnea Fletcher - Training Technicians for the Biotechnology Industry
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Linnea Fletcher, Biotechnology Department chair at Austin Community College and Director of the InnovATEBIO National Biotechnology Education Center, discusses training technicians to tackle real world challenges in the biotechnology industry. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biolo…
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Yuri Deigin - Partial Reprogramming Drug Development for Aging
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Yuri Deigin, co-founder of YouthBio Therapeutics, discusses developing rejuvenation gene therapies based on partial reprogramming and his role reinvigorating investigations into the origins of SARS-CoV-2. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, w…
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Adam Freund - targeting cells to treat disease
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Adam Freund, founder and CEO of Arda Therapeutics, discusses how targeted killing of pathogenic cells could be used to treat chronic disease and aging. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscr…
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Alfredo Andere - connecting biologists and bioinformaticians
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Alfredo Andere, co-founder and CEO of Latch Bio, discusses the unique challenges facing young entrepreneurs and the future of cloud computing in biology. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformatics…
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Joshua Hare - cell-based therapies for aging
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Joshua Hare, Professor of Medicine at the University of Miami and co-founder of Longeveron, discusses the regenerative and reparative potential of MSCs and how cell therapies will revolutionize medicine. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, wi…
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Alex Shalek - new technology for systems biology
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Alex Shalek, Associate Professor of Chemistry at MIT, discusses new methods and technologies in systems biology that have enabled advances in the diagnosis and treatment of autoimmune diseases and cancer. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, w…
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Jamie Smyth - heart disease and viral infection
31:06
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Jamie Smyth, Associate Professor at Virginia Tech, discusses intercellular communication in the heart and how viral infection of cardiac cells can result in heart disease. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://…
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Amar Gajjar - pediatric brain cancer
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Amar Gajjar, world-renowned neuro-oncologist and chair of the Department of Pediatric Medicine at St. Jude Children's Research Hospital, discusses emerging treatments for pediatric brain tumors such as medulloblastoma. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnolog…
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Jill Reckless & Jon Heal - outsourcing drug development
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Jill Reckless, CEO and co-founder of RxCelerate, and Jon Heal, Head of In Silico Designs at RxCelerate, discuss the virtual biotech industry, outsourcing drug development, and using bioinformatics for target optimization. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechno…
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Adam Siepel - evolutionary genomics
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Adam Siepel, Professor of quantitative biology at Cold Spring Harbor Laboratory, discusses the applications of evolutionary genomics in anthropology, infectious disease, and cancer. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics…
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Erich Jarvis - genomics of vocal learning
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Erich Jarvis, Professor at The Rockefeller University and investigator at HHMI, explains how studying the neural and genetic mechanisms of vocal learning in songbirds gives insights into the development of spoken language in humans. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs o…
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Mauro Calabrese - long non-coding RNA
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Mauro Calabrese, Associate Professor at UNC Chapel Hill and Director of Graduate Studies in the Department of Pharmacology, discusses the future of RNA-based therapeutics and the role of lncRNA in gene transcription. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology …
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Damian Kao, COO of Basepaws, discusses the challenges B2C science and the future of consumer genomics in cats, from microbiome to epigenetic testing. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.…
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Nicholas Heaton - influenza & SARS-CoV-2
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Nicholas Heaton, Assistant Professor of molecular genetics and microbiology at Duke University School of Medicine, talks about influenza, SARS-CoV-2, and potential future pandemics. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics…
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Becca Chodroff Foran - consumer genetics for dogs
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Becca Chodroff Foran, Head of R&D at Wisdom Panel, describes the recent advances in pet genomics and how we can use genetic data from dogs to guide research on human health. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https:…
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Stacy Horner - flaviviruses and SARS-CoV-2
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Stacy Horner, associate professor of molecular genetic and microbiology at Duke University Medical School, compares hepatitis C and dengue virus to SARS-CoV-2 and suggests policy changes to make academia more inclusive. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnolo…
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Jason Arnold - microbiome core facilities
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Jason Arnold, Technical Director of the Microbiome Core Facility at UNC Chapel Hill, describes methods of improving the scientific rigor of microbiota research and his experiences as a snake breeder. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a…
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Bettina Hein - managing chronic illness with AI
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Bettina Hein, CEO and founder of juli, is a serial tech entrepreneur, using artificial intelligence to help people manage symptoms of chronic illness. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro…
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Bharath Ramsundar - applications of AI
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Bharath Ramsundar, founder and CEO of Deep Forest Sciences, described many applications of artificial intelligence in biotech, society, and the military. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformatics…
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Saroja Voruganti - nutrition and genetics
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Saroja Voruganti, Associate Professor at UNC Chapel Hill, shares her passion for nutrition as she discusses the fields of nutrigenetics and nutrigenomics. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformatic…
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Jon Chee - equipment leasing for life sciences
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Jon Chee, co-founder and CEO of Excedr, shares his experience founding a life sciences equipment leasing company before the latest biotech boom. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Ian Carroll - the intestinal microbiota
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Ian Carroll, assistant professor of nutrition at the University of North Carolina, Chapel Hill, describes the relationship between the intestinal microbiota and eating disorders. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. h…
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Mark Kotter - stem cell programming
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Mark Kotter, co-founder and CEO of Bit Bio, discusses the uses of reprogrammed human cells in research and drug development. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Matthias Gromeier - viral cancer therapeutics
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Matthias Gromeier, professor of neurosurgery at Duke University, describes how his breakthrough therapeutic combines poliovirus and rhinovirus to eliminate brain cancers. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://w…
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Carolyn Coyne - immunity in the placenta
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Carolyn Coyne, professor of Molecular Genetics and Microbiology at Duke University, discusses how pathogens can subvert cellular barriers in the placenta and gut to cause disease. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. …
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Bryan Cullen, director of Duke University’s Center for Virology, describes how viruses use microRNAs, epigenetics, and epitranscriptomics to regulate their biology. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bio…
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Micah Luftig - Epstein-Barr virus and cancer
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Micah Luftig, associate professor and vice-chair of Molecular Genetics and Microbiology at Duke University, explains how Epstein-Barr virus can induce tumorigenesis and how is father inspired him to become a virologist. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnolo…
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Jim Ray - treating Alzheimer's disease
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Jim Ray, head of MD Anderson's Neurodegeneration Consortium, explains new perspectives in Alzheimer's disease research and shares his experience in biotech, pharma, and academia. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. h…
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Fernando Martinez - anti-aging drug development
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Fernando Martinez, senior scientist at Fountain Therapeutics, uses AI and phenotypic screening to discover drugs that reduce the signs of aging. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Jeremy Kamil - SARS-CoV-2 genetics with guest host Razib Khan
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Jeremy Kamil, associate professor of microbiology at LSU Health Shreveport, discusses the genetics of SARS-CoV-2, variants, and vaccines with guest host Razib Khan. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bio…
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Adam Robertson - broad-spectrum cancer therapeutics
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Adam Robertson, CSO of Hemispherian, talks about developing cancer therapeutics in an Oslo-based startup. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Brett Abrahams - drug development and neurogenomics
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Brett Abrahams, Executive VP of R&D at Magnolia Neurosciences, discusses his work on chemotherapy-induced peripheral neuropathy and other brain disorders. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformatic…
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Noor Siddiqui - preimplantation screening with polygenic risk scores
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We spoke with Noor Siddiqui about how Orchid is using polygenic risk scores for common diseases for preimplantation screening. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro.com/…
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Matthew Holt - astrocyte biologist
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Matthew Holt, neuroscience professor at VIB-KU Leuven, explains the role of glial cells in neurodegenerative diseases and discusses boxing and motorbike racing. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinfo…
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Lucia Huang & Jimmy Qian - mental health tech
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Lucia and Jimmy, co-founders of Osmind, discuss psychedelic therapies for mental illness, the future of the Bay Area, and public benefit corporations. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinformaticscro…
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Grant Belgard - remote work in biotech
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Our regular host, Grant Belgard, founder of The Bioinformatics CRO, talks about his career working remotely and how he expects technology to change the biotech industry. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://ww…
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Ambika Bumb - from nanotech to government service
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We talk with Ambika Bumb, science and technology advisor to the department of state’s crisis management and strategy team, about nanotechnology, the pandemic, and biotech start-ups. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics…
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Lucas Steuber - mindreading with BCIs and AR
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We talk with Lucas Steuber, clinical product and marketing director at Cognixion, about using a brain-computer interface and augmented reality to help people with speech disabilities communicate. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a foc…
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Trevor Martin - CRISPR diagnostics for COVID-19
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We talk with Trevor Martin, co-founder and CEO of Mammoth Biosciences, about using CRISPR technology to detect SARS-CoV-2, his experience as a new CEO, and science education. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https…
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Dan Geschwind - precision medicine
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Dan Geschwind, professor and associate vice chancellor at UCLA, shares his path to neuroscience, thoughts on precision medicine, and why one should use unbiased methods to prioritize hypotheses. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focu…
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Deepti Gurdasani, Christina Pagel & Nisreen Alwan - why vaccines may not end the COVID pandemic
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In our first panel discussion, three COVID experts share their thoughts on emerging variants of SARS-CoV-2 and the growing selective pressures for immune escape. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinf…
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Delian Asparouhov - space manufacturing
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Delian Asparouhov, co-founder of Varda Space Industries and principal at Founders Fund, talks about space manufacturing, economic bubbles, and tech investing. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on genomics. https://www.bioinform…
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Vay Cao - Free the PhD, work beyond academia
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We chat with Vay Cao, founder of Free the PhD, about her journey from neuroscience to an MSL-like role and how PhDs can leverage their experiences to get that first job outside academia. The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of biotechnology companies, with a focus on gen…
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Mark DePristo - designing antibodies with machine learning
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We talk with Mark DePristo, founder and CEO of BigHat Biosciences, about building better antibody therapeutics using machine learning, overcoming the fear of failure, and the pros and cons of working in academia, for large companies like Google, and at a biotech start up. The Bioinformatics CRO is a fully distributed contract research company that …
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Shaan Gandhi - biotech venture capital
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We talk with Shaan Gandhi, Director at Northpond Ventures, about the intersections of science, medicine, and business and how his training as an internist has colored his experience in venture capital. (Recorded on January 18, 2021) The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs o…
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Peter Joyce - founding a virtual biotech
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We talk with Peter Joyce, co-founder and CEO of Grey Wolf Therapeutics, about novel cancer therapies, running a virtual biotech company, and encouraging a new generation of well-rounded scientists. (Recorded on December 16, 2020) The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology needs of b…
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Adam Marblestone - scientific moonshots
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We talk with Adam Marblestone about his work with moonshot science and technology projects, exciting advances in nanotechnology and AI, and his PhD work using expansion microscopy to map neural connections. (Recorded on December 18, 2020) The Bioinformatics CRO is a fully distributed contract research company that serves the computational biology n…
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