We spend a third of our lives sleeping, and this podcast is all about understanding sleep. We know a lot about what the brain does in sleep, but we are just starting to understand why it does some of these things, and even more excitingly, how we can take full advantage of sleep and also manipulate it for our own ends. In each episode, neuroscientist Penny Lewis interviews a different sleep researcher, talking about a various aspect of sleep science. Topics will include sleep physiology and ...
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S2E9 - End of season Q&A Session
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For our end of season special, we have the rest of the NaPS lab in to answer a number of exciting sleep-related questions from our listeners. These touch on a range of different subjects from sleeps involvement in weight gain to alcohol's effect on sleep. Thanks to those who sent in questions! List of Questions: 1. What is it in general anaesthetic…
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S2E8 - Chiara Cirelli - Synaptic Homeostasis in Sleep
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In this episode, we talk with Professor Chiara Cirelli from the department of Psychiatry at the University of Wisconsin. We begin by hearing about how she first got interested in sleep research, and particularly about her time as a medical student at the University of Pisa where she worked on the noradrenergic system using cat models. We then look …
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S2E7 - Reto Huber - Local Sleep, Sleep Homeostasis, & Brain Plasticity
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In this episode, we interviewed Professor Reto Huber, who leads a research group at the University Children’s Hospital, Zurich. Reto’s interests encompass sleep disorders, development, synaptic plasticity and regeneration. In this episode we discuss local sleep, a process whereby different parts of the brain express different depths of sleep or wak…
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S2E5 - Manuel Schabus & Kerstin Hoedlmoser - How babies sleep and what this means for their cognitive function
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In this episode we talk to Professor Manuel Schabus and Professor Kerstin Hoedlmoser from the Centre for Cognitive Neuroscience at the University of Salzburg. In this episode, we discuss their work on the development of sleep-in babies, first discussing what baby sleep is like and how it differs from older children and adults in regard to activity …
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S2E6 Wenbiao Gan - The role of sleep in synapse formation and elimination
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In this episode, we talk to Professor Wenbiao Gan from the Neuroscience and Physiology and Skirball Institute at New York University School of Medicine. Professor Gan tells us about how he started to become interested in studying sleep and its impact on learning and memory. He talks about intriguing and hands-on ways to assess the formation and eli…
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S2E4 Colin Espie – What is insomnia and how can we treat it?
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In this episode, we interviewed Colin Espie, one of the world’s leading authorities on sleep and insomnia. Colin is Professor in Sleep Medicine at the University of Oxford, and Clinical Director of the Experimental & Clinical Sleep Medicine Programme, Sleep & Circadian Neurosciences Institute, again at the University of Oxford. Professor Espie talk…
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S2E3 - Tore Nielsen & Mark Blagrove - Lucid Dreaming & the 'Dream-lag' effect
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In this episode, we talk to Professor Tore Nielsen from the University of Montreal and Professor Mark Blagrove from Swansea University. In part 2 of this two part episode, we carry on our discussion about nightmares and talk about Tore's work on imagery rehearsal. A process where the dreamer rehearses their nightmares finding solutions to them in w…
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S2E1:Tristan Bekinschtein - The Consciousness Boundary
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In this episode, we talk to Dr Tristan Bekinschtein from the Cambridge Consciousness and Cognition Lab and discuss his research looking into the boundary between consciousness and unconsciousness. We talk about his work in the loss of consciousness in vegetative state patients, sedation and sleep and his findings regarding brain markers which indic…
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S2E2: Tore Nielsen & Mark Blagrove - Part 1 - What we dream and why we need to
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In this episode, we talk to Professor Tore Nielsen from the University of Montreal and Professor Mark Blagrove from Swansea University. In part 1 of this two part episode, we talk about how both our guests became interested in the world of sleep and dreams and then discuss what we actually dream about, from emotional REM dreams to non-rem dreams. W…
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Episode 10: Christmas Q&A session
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Today's episode is a little bit different. We're marking the end of our first season by roping in the rest of the NaPS lab to answer listeners' sleep-related questions. Thanks to everyone who sent questions in! List of questions: Why do we use the term ‘sleeping like a baby’ when babies don’t, in fact, sleep? - From Jaime Jenkins How do hormones af…
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Episode 9: Michelle Carr and Karen Konkoly - What is lucid dreaming and how can it help us?
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Have you ever wished you could control your dreams? In this episode we learn about new approaches letting people do exactly that. We also delve into important benefits lucid dreaming could have, such as helping reduce nightmares or helping process traumatic memories. In addition, we explore how lucid dreams provide a window into understanding consc…
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Episode 8: Daniel Bendor: Memory Replay and Consolidation in Rodents
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In this episode, we talk to Dr Daniel Bendor from University College London. Daniel's work focuses on rodent studies of place cells in the hippocampus. We discuss the phenomena of memory replay in which place cell activity mimics patterns of activity that occurred while the rodent was performing a task in wake. We also discuss how this process can …
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Episode 7: Björn Rasch -Targeted Memory Reactivation
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In this episode, we talk to Professor Björn Rasch about the pioneering of a process called Targeted Memory Reactivation (TMR). TMR is a tool which can be used to selectively consolidate learnt material during sleep by pairing it with sensory stimuli such as odours or sounds during learning. This process can be used to manipulate memories during sle…
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Episode 6: Dan Margoliash & Tim Brawn: How sleep helps birds to learn their songs
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In this episode we take a neuroethological approach to sleep, and discover why songbirds are such a good model system for studying sleep's role in learning. These include advantages like songbirds' sleep-wake patterns and sleep architecture being more similar to human's than rodents', the fact that songbirds are strongly motivated to learn their so…
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Episode 5: Anat Arzi & Thomas Andrillon - Learning in your sleep
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We humans have long wondered if it is possible to learn while we sleep but, experimental findings on this have often been disappointing. You will now be happy to learn that the tide has turned in this respect, since we now have firm proof that it IS indeed possible to learn new information while you sleep. However - the information your brain can p…
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Episode 4: Vlad Vyazovskiy - Local sleep, circadian rhythms and torpor
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In this episode we examine how sleep differs between species to get some clues about what sleep actually is as a phenomenon. How have marine animals solved the problem of sleeping when they regularly need to come up for air? And how do amphibians adapt their sleep architecture from life at sea to life on the land? What can mice running on their whe…
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Episode 3: Gina Poe - How sleep restructures our memories and emotions
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In this episode we ask Gina Poe, a sleep scientist from UCLA, about her seminal work on both REM and non-REM sleep. We talk about the role of memory replay in REM, how to measure such replay in rats, as well as the ways in which REM impacts upon emotional representations, and may even help us to combat post traumatic stress disorder (PTSD). We also…
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Episode 2: Sasha Handley - A history of sleep in Early Modern England
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In this episode we look back on the beliefs and practices people had around sleep in the 16th-18th centuries. We learn about why sleep was thought so important for health, how various habits and superstitions arose around sleep often rooted in medicine or religion, and how the bedroom became a symbol of status and power. We also cover how the elect…
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Episode 1: Bob Stickgold - What do sleep and dreams do for our minds and our memories?
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In this episode, we speak with Professor Bob Stickgold, one of the most prominent researchers in the field of sleep science. Bob tells us about the early days of sleep research and how he and other scientists struggled to convince the world that sleep really is important for memory. He also talks about methodological subtleties to investigate the r…
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